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News

15 May 2020

Instruct-ERIC Call for R&D Pilot Project Awards is now Open

Instruct-ERIC invites applications for its sixth Research & Development (R&D) Pilot Project Awards. Recipients of the Instruct R&D Award receive up to €15,000 for a basic or applied research project lasting approximately one year. The expectation is that the preliminary data from pilot project will form the basis for recipients to apply for more substantial funding through conventional routes. Proposal submission is open until 31 August 2020.

13 May 2020

Successful Installation of World’s First 1.2 GHz NMR System Enables Novel Functional Structural Biology Research

On May 4, 2020, Bruker Corporation announced the successful installation and customer acceptance of the world’s first Avance™ NEO 1.2 GHz NMR system at the CERM of the University of Florence. This new 1.2 GHz NMR system will enable CERM to perform novel research in functional structural biology of proteins and protein complexes.

11 May 2020

Visualizing an unseen enemy; mobilizing structural biology to counter COVID-19

Edward N. Baker from School of Biological Sciences, University of Auckland, New Zealand, has published an editorial in a number of IUCr Journals [see also Baker, E. N. (2020). IUCrJ. 7, 366–367; Baker, E. N. (2020). Acta Cryst. D76, 311–312] to highlight the work of structural biologists in fighting COVID-19. At the end of his short recollection he emphasizes: “My purpose in writing this editorial, however, is to applaud the energy and skill of the researchers, and their public spirit in sharing their results. And I take a vicarious pride in the fact that the discipline to which I have given my professional life – crystallography – has such an important role at a time of international crisis.”

15 Apr 2020

On the SARS-Cov-2 Inhibitor Track

To develop specific anti-coronavirus therapeutics and prophylactics, the molecular mechanism that underlies viral infection must first be defined. The recent study published in Cell Research solved the X-ray crystal structure of six-helical bundle (6-HB) core of the HR1 and HR2 domains in the SARS-CoV-2 S protein S2 subunit, revealing that several mutated amino acid residues in the HR1 domain may be associated with enhanced interactions with the HR2 domain, as compared to SARS-CoV.

14 Apr 2020

Instruct-ERIC Resource Centre – Supporting research relating to SARS-CoV-2 and COVID-19

Instruct-ERIC has put together a catalogue of tools, information and support that is available from Instruct and the wider scientific community to support COVID-19 research Many Instruct-ERIC services are available via remote access, where samples can be sent for analysis without the need for researchers to travel.

7 Apr 2020

The 2020 Petr Sedmera Award

for the best published work in Nuclear Magnetic Resonance knows its winner. The competition is organized by the Czech Spectroscopic Society of Jan Marcus Marci and sponsored by the pharmaceutical company Teva. The awarded paper Quantitative Conformational Analysis of Functionally Important Electrostatic Interactions in the Intrinsically Disordered Region of Delta Subunit of Bacterial RNA Polymerase was published in Journal of the American Chemical Society by Lukáš Žídek and co-workers from CEITEC, Masaryk University.

Newsletters

Reader's Corner Archive

2 Jun 2017

The 3rd Instruct Biennial Structural Biology Conference

The 3^rd Instruct Biennial Structural Biology Conference took place in Brno, Czech Republic, from May 24 to May 26, 2017 hosted by Instruct-CZ/CEITEC. Brno is the city of Johann Gregor Mendel, a founder of modern genetics and one of the first scientists who applied a multidisciplinary approach to explain his observations. The social programme of the meeting included a visit to the Mendel’s Museum and dinner at the Augustinian Abbey, where Mendel worked and lived.