The 5th Workshop of Structural Biology in the Helmholtz Association
The workshop will take place at the DKFZ in Heidelberg, from December 17 to December 18, 2019
Postdoc and PhD Positions in Biomolecular NMR spectroscopy - Selenko lab at the Weizmann Institute of Science
Postdoc and PhD positions in biomolecular NMR spectroscopy are available in the Selenko Lab at the Weizmann Institute of Science, Department of Biological Regulation.
PDB-Dev: A Prototype System for Depositing Integrative/Hybrid Structural Models
announced in 2017 contains now 22 officially released structures.
Reader’s Corner - literature to read, science to follow
As of July 2019, a new section Reader’s Corner - literature to read, science to follow has been added to our web.
eBIC Cryo-EM Sample preparation course 13th-15th Nov 2019
Registration for course at Diamond Light Source, UK is now open.
Extended Abstract Deadline for "New Frontiers in Structure-Based Drug Discovery" Conference
International conference on New Frontiers in Structure-Based Drug Discovery in Florence, Italy extended deadline for abstracts to July 15, 2019.
Call for proposals for 7th Instruct Internship Programme
Call for proposals for Instruct Internship Programme (for internships to be held in 2019-2020) is now open.
New combined AFM-Raman microscope at CEITEC MU
The new instrument equipped at the Nanobiotechnology Core Facility, CEITEC MU.
Reader's Corner Archive
Principles for Integrative Structural Biology Studies
Guru of integrative structural biology computation Andrej Sali and Michale P. Rout summarize in the recent Cell Primer Principles for Integrative Structural Biology Studies.
Potential of cryo-EM for high-resolution structural analysis of gap junction channels
The review by Oshima et. al. in Current Opinions in Structural Biology outlines structural biology of gap junction channels utilizing crystallography and single-particle cryo-EM to shed light on the functional mechanisms of cell-cell communication that are essential for multicellular organisms.
Molecular dynamics simulations of macromolecular crystals
The paper of David Case and David Cerutti in WIREs Computational Molecular Science evaluates past fusions of simulations and crystallography and looks ahead to the ways that simulations of crystal structures will enhance structural biology in the future.
Combining Mass Spectrometry (MS) and Nuclear Magnetic Resonance (NMR) Spectroscopy for Integrative Structural Biology of Protein–RNA Complexes
In this publication Fred Allain et.al. reviews recent advances in hybrid structural approaches with a focus on combining MS analysis of cross-linked protein–RNA complexes and NMR spectroscopy.
Quo Vadis Biomolecular NMR Spectroscopy?
In Quo Vadis Biomolecular NMR Spectroscopy? Phil Selenko reviews recent methodological spin-off applications whose developments were stimulated by cellular NMR approaches.
Essay on Biomembrane Structure
Christoph Gerle provides historical outline of how we arrived at our current understanding of biomembranes and the models we use to describe them in Essay on Biomembrane Structure. A selection of direct experimental findings on the nano-scale structure of biomembranes is taken up to discuss their physical nature, and special emphasis is put on the surprising insights that arise from atomic scale descriptions.
Role of integrative structural biology in understanding transcriptional initiation
Role of integrative structural biology in understanding transcriptional initiation is discussed by Philip Robinson et. al. in a review, which presents a general background to integrative structural biology, describes of how it should be practically implemented, and shows how it has furthered our understanding of the biology of large transcriptional assemblies.
Frontiers in Cryo Electron Microscopy of Complex Macromolecular Assemblies
In this publication Sriram Subramaniam et. al. report on structural studies of G protein–coupled receptors, spliceosomes, and fibrillar specimens and illustrate the progress made by advanced cryo-EM methods.