Page 53: News | Czech Infrastructure for Integrative Structural Biology

News

1 Jun 2020

Cryo-EM reaches yet another milestone – Comments on two recent cryo-EM atomic resolution studies

Two studies published during last two weeks have reported that single particle cryo-EM data can be now resolved to 1.20Å or 1.25Å, respectively. The groups of Sjors H.W. Scheres (LMB-MRC, Cambridge) and Holger Stark (MPI Göttingen) have for the first time shown that atomic resolution is attainable by single particle cryo-EM.

27 May 2020

EOSC-Life Training Call Opportunity

The EOSC-Life Training team offers funding to support training activities and provides expertise and guidance to help you organise successful and impactful training through our Training Open Call.

27 May 2020

Single-particle cryo-EM at atomic resolution

A. Radu Aricescu & Sjors H.W. Scheres et al. show in the bioRxiv paper that using a new electron source, energy filter and camera, a 1.7 Å resolution cryo-EM reconstruction for a prototypical human membrane protein, the β3 GABAA receptor homo-pentamer, can be obtained.

25 May 2020

Breaking the next Cryo-EM resolution barrier – Atomic resolution determination of proteins!

In a new bioRxiv paper, Holger Stark et a. report a 1.25 Å resolution structure of apoferritin obtained by cryo-EM with a newly developed electron microscope providing unprecedented structural details. Their apoferritin structure has almost twice the 3D information content of the current world record reconstruction (at 1.54 Å resolution). For the first time in cryo-EM they can visualize individual atoms in a protein, see density for hydrogen atoms and single atom chemical modifications.

18 May 2020

PostEra Call: Help us Fight Coronavirus - Contribute your expertise to design inhibitors of the SARS-CoV-2 main protease

An international group of scientists from academia and industry is seeking opportunities to contribute to combatting COVID-19. They welcome contributions of many forms including scientific expertise, experimental capabilities, and indeed donations to make this possible.

18 May 2020

Highlights of Coronavirus Structural Studies

The CIISB website introduces a new section entitled „Highlights of Coronavirus Structural Studies“. This section presents the latest and most important results of structural studies of SARS-CoV-2 and its constituents. Its content will be updated regularly.

Newsletters

Reader's Corner Archive

2 Jun 2017

The 3rd Instruct Biennial Structural Biology Conference

The 3^rd Instruct Biennial Structural Biology Conference took place in Brno, Czech Republic, from May 24 to May 26, 2017 hosted by Instruct-CZ/CEITEC. Brno is the city of Johann Gregor Mendel, a founder of modern genetics and one of the first scientists who applied a multidisciplinary approach to explain his observations. The social programme of the meeting included a visit to the Mendel’s Museum and dinner at the Augustinian Abbey, where Mendel worked and lived.