Publications written with support of CIISB

Acknowledgement

CIISB, Instruct-CZ Centre of Instruct-ERIC EU consortium, funded by MEYS CR infrastructure project LM2023042 and European Regional Development Fund-Project „UP CIISB“ (No. CZ.02.1.01/0.0/0.0/18_046/0015974), is gratefully acknowledged for the financial support of the measurements at the CF [name of the unit/CF].

Or in a short version: We acknowledge CF [name of the unit/CF] of CIISB, Instruct-CZ Centre, supported by MEYS CR (LM2023042) and European Regional Development Fund-Project „UP CIISB“ (No. CZ.02.1.01/0.0/0.0/18_046/0015974).

Publications written with support of CIISB

2024

D. Arbon, et al.: Chelation of Mitochondrial Iron as an Antiparasitic Strategy, ACS Infect. Dis., 10 (2024) 676-687, 10.1021/acsinfecdis.3c00529

A. Dhillon, et al.: Structural insights into the interaction between adenovirus C5 hexon and human lactoferrin, Journal of Virology, (2024) 19, 10.1128/jvi.01576-23

M. Gajarsky, et al.: DNA Quadruplex Structure with a Unique Cation Dependency, Angewandte Chemie-International Edition, (2024) 11, 10.1002/anie.202313226

V.V. Hausnerová, et al.: RIP-seq reveals RNAs that interact with RNA polymerase and primary sigma factors in bacteria, Nucleic Acids Res., (2024) 23, 10.1093/nar/gkae081

M. Charousova, et al.: Engineered human H-chain ferritin with reversed charge of the internal cavity exhibits RNA-mediated spongelike effect for loading RNA/DNA-binding molecules, Biomater. Sci., 12 (2024) 1249-1262, 10.1039/d3bm01257c

L. Kavcic, et al.: From structural polymorphism to structural metamorphosis of the coat protein of flexuous filamentous potato virus Y, Comm. Chem., 7 (2024) 19, 10.1038/s42004-024-01100-x

M. Kejik, et al.: Lewis Acidic Aluminosilicates: Synthesis, <SUP>27</SUP>Al MQ/MAS NMR, and DFT-Calculated <SUP>27</SUP>Al NMR Parameters, Inorganic Chemistry, 63 (2024) 2679-2694, 10.1021/acs.inorgchem.3c04035

T. Mujawar, et al.: A Platform for the Synthesis of Oxidation Products of Bilirubin, Journal of the American Chemical Society, 146 (2024) 1603-1611, 10.1021/jacs.3c11778

M. Polak, et al.: Isotopic Depletion Increases the Spatial Resolution of FPOP Top-Down Mass Spectrometry Analysis, Anal. Chem., 96 (2024) 1478-1487, 10.1021/acs.analchem.3c03759

P. Vankova, et al.: Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants, Febs Letters, (2024) 15, 10.1002/1873-3468.14800

J. Czubinski, et al.: pH-Dependent oligomerisation of γ-conglutin: A key element to understand its molecular mechanism of action, Food Hydrocolloids, 147 (2024) 12, 10.1016/j.foodhyd.2023.109386

Z. Bielková, et al.: Zero-field splitting in tetracoordinate Co(II) complexes containing heterocyclic aromatic ligands, J. Mol. Struct., 1295 (2024) 9, 10.1016/j.molstruc.2023.136667

Š. Klimovič, et al.: Hyaluronic acid-based hydrogels with tunable mechanics improved structural and contractile properties of cells, Biomaterials Advances, (2024) 159, 10.1016/j.bioadv.2024.213819

2023

A. Del Mauro, et al.: Merging Bambus 6 uril and Biotin 6 uril into an Enantiomerically Pure Monofunctionalized Hybrid Macrocycle, Organic Letters, 26 (2023) 106-109, 10.1021/acs.orglett.3c03715

B. Klodová, et al.: Regulatory dynamics of gene expression in the developing male gametophyte of Arabidopsis, Plant Reprod., 36 (2023) 213-241, 10.1007/s00497-022-00452-5

E. Koutná, et al.: Multivalency of nucleosome recognition by LEDGF, Nucleic Acids Res., (2023) 15, 10.1093/nar/gkad674

P. Pourali, et al.: Conjugation of microbial-derived gold nanoparticles to different types of nucleic acids: evaluation of transfection efficiency, Sci Rep, 13 (2023) 14, 10.1038/s41598-023-41567-7

A. Ramundo, et al.: Visible-Light-Activated Carbon Monoxide Release from Porphyrin-Flavonol Hybrids, Journal of the American Chemical Society, 146 (2023) 920-929, 10.1021/jacs.3c11426

S.H. Sun, et al.: Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease, Nature, 624 (2023) 653-+, 10.1038/s41586-023-06776-0

A.K. Tonduru, et al.: Targeting Glial Cells by Organic Anion-Transporting Polypeptide 1C1 (OATP1C1)-Utilizing <sc>l</sc>-Thyroxine-Derived Prodrugs, J. Med. Chem., 66 (2023) 15094-15114, 10.1021/acs.jmedchem.3c01026

S. Albani, et al.: Determination and Kinetic Characterization of a New Potential Inhibitor for AmsI Protein Tyrosine Phosphatase from the Apple Pathogen Erwinia amylovora, Molecules, 28 (2023) 11, 10.3390/molecules28237774

M. Maly, et al.: Tetracycline-modifying enzyme SmTetX from Stenotrophomonas maltophilia, Acta Crystallogr. F-Struct. Biol. Commun., 79 (2023) 180-192, 10.1107/s2053230x23005381

M. Forinová, et al.: A comparative assessment of a piezoelectric biosensor based on a new antifouling nanolayer and cultivation methods: Enhancingi S. aureus detection in fresh dairy products, Curr. Res. Biotechnol., 6 (2023) 6, 10.1016/j.crbiot.2023.100166

T. Pokorny, et al.: Copper Phosphinate Complexes as Molecular Precursors for Ethanol Dehydrogenation Catalysts, Inorganic Chemistry, 62 (2023) 19871-19886, 10.1021/acs.inorgchem.3c01678

M. Nemergut, et al.: Illuminating the mechanism and allosteric behavior of NanoLuc luciferase, Nature Communications, 14 (2023) 20, 10.1038/s41467-023-43403-y

A. Kertisová, et al.: Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation, Open Biol, 13 (2023) 14, 10.1098/rsob.230142

J. Blahut, et al.: Optimal control derived sensitivity-enhanced CA-CO mixing sequences for MAS solid-state NMR - Applications in sequential protein backbone assignments, J. Magn. Reson. Open, 16-17 (2023) 9, 10.1016/j.jmro.2023.100122

Q.L. Long, et al.: The phosphorylated trimeric SOSS1 complex and RNA polymerase II trigger liquid-liquid phase separation at double-strand breaks, Cell Reports, 42 (2023) 25, 10.1016/j.celrep.2023.113489

I. Doroshenko, et al.: Structurally diverse copper(II) phosphonates: Synthesis, structure, and magnetism, Polyhedron, 246 (2023) 11, 10.1016/j.poly.2023.116694

M. Chvojka, et al.: Tuning CH Hydrogen Bond-Based Receptors toward Picomolar Anion Affinity via the Inductive Effect of Distant Substituents, Angewandte Chemie-International Edition, (2023) 7, 10.1002/anie.202318261

V. Kundrat, et al.: W18O49 Nanowhiskers Decorating SiO2 Nanofibers: Lessons from In Situ SEM/TEM Growth to Large Scale Synthesis and Fundamental Structural Understanding, Cryst. Growth Des., 24 (2023) 378-390, 10.1021/acs.cgd.3c01094

M. Cassani, et al.: YAP Signaling Regulates the Cellular Uptake and Therapeutic Effect of Nanoparticles, Adv. Sci., (2023) 16, 10.1002/advs.202302965

K. Snajdarova, et al.: Atypical homodimerization revealed by the structure of the (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum, Acta Crystallogr. Sect. D-Struct. Biol., 79 (2023) 956-970, 10.1107/s2059798323006642

K. Baishya, et al.: Bio-AFM exploits enhanced response of human gingival fibroblasts on TiO2 nanotubular substrates with thin TiO2 coatings, Appl. Surf. Sci. Adv., 18 (2023) 12, 10.1016/j.apsadv.2023.100459

P. Svec, et al.: Corynebacterium antarcticum sp. nov., Corynebacterium marambiense sp. nov., Corynebacterium meridianum sp. nov., and Corynebacterium pygosceleis sp. nov., isolated from Adelie penguins (Pygoscelis adeliae), Syst. Appl. Microbiol., 46 (2023) 14, 10.1016/j.syapm.2022.126390

J.L. Pacheco-García, et al.: Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme, Febs Journal, 290 (2023) 1855-1873, 10.1111/febs.16677

M. Frolikova, et al.: Juno and CD9 protein network organization in oolemma of mouse oocyte, Front. Cell. Dev. Biol., 11 (2023) 16, 10.3389/fcell.2023.1110681

E. Koutná, et al.: Multivalency of nucleosome recognition by LEDGF, Nucleic Acids Res., (2023) 15, 10.1093/nar/gkad674

A. Sadzak, et al.: Puncturing lipid membranes: onset of pore formation and the role of hydrogen bonding in the presence of flavonoids, J. Lipid Res., 64 (2023) 14, 10.1016/j.jlr.2023.100430

K. Látrová, et al.: R-Type Fonticins Produced by Pragia fontium Form Large Pores with High Conductance, J. Bacteriol., 205 (2023) 15, 10.1128/jb.00315-22

A.C. Papageorgiou, et al.: Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase, Nature Communications, 14 (2023) 19, 10.1038/s41467-023-42503-z

G. Das, et al.: Targeting Prostate Cancer Using Bispecific T-Cell Engagers against Prostate-Specific Membrane Antigen, ACS Pharmacol. Transl. Sci., 6 (2023) 1703-1714, 10.1021/acsptsci.3c00159

K. Jelínková, et al.: Two Squares in a Barrel: An Axially Disubstituted Conformationally Rigid Aliphatic Binding Motif for Cucurbit 6 uril, Journal of Organic Chemistry, (2023) 11, 10.1021/acs.joc.3c01556

V. Evic, et al.: Evolutionarily conserved cysteines in plant cytosolic seryl-tRNA synthetase are important for its resistance to oxidation, Febs Letters, (2023) 18, 10.1002/1873-3468.14748

K. Chmelova, et al.: Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography, Protein Sci., 32 (2023) 22, 10.1002/pro.4751

E. Chocholova, et al.: Extraction Protocol for Parallel Analysis of Proteins and DNA from Ancient Teeth and Dental Calculus, Journal of Proteome Research, 22 (2023) 3311-3319, 10.1021/acs.jproteome.3c00370

V. Kovarovic, et al.: Staphylococcus brunensis sp. nov. isolated from human clinical specimens with a staphylococcal cassette chromosome-related genomic island outside of the rlmH gene bearing the ccrDE recombinase gene complex, Microbiol. Spectr., (2023) 22, 10.1128/spectrum.01342-23

A. Kunka, et al.: Advancing Enzyme's Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning, Acs Catalysis, 13 (2023) 12506-12518, 10.1021/acscatal.3c02575

T. Lambert, et al.: Development of a PNGase Rc Column for Online Deglycosylation of Complex Glycoproteins during HDX-MS, J. Am. Soc. Mass Spectrom., (2023) 11, 10.1021/jasms.3c00268

P. Machac, et al.: Non-hydrolytic sol-gel synthesis of zirconium phosphonates with controlled mesoporosity, Microporous Mesoporous Mat., 362 (2023) 10, 10.1016/j.micromeso.2023.112787

E. Raudonyte-Svirbutaviciene, et al.: Tailoring hydroxyapatite morphology via the effect of divalent cations on the hydrolysis of a-TCP: Oriented crystal growth towards the application in water treatment, Ceram. Int., 49 (2023) 32816-32825, 10.1016/j.ceramint.2023.07.252

D. Skoda, et al.: Propylene Metathesis over Molybdenum Silicate Microspheres with Dispersed Active Sites, Acs Catalysis, 13 (2023) 12970-12982, 10.1021/acscatal.3c02045

J. Dohnalek, et al.: The role of the HelD protein in bacterial transcription and antibiotic resistance, Eur. Biophys. J. Biophys. Lett., 52 (2023) S77-S77

D.D. Dochain, et al.: Non-hydrolytic Sol-Gel Routes to Bifunctional Cu-Ta-SiO2 Catalysts for the Upgrading of Ethanol to Butadiene, Chem. Mat., 35 (2023) 7113-7124, 10.1021/acs.chemmater.3c01407

M. Dzurov, et al.: A thermosensitive gel matrix for bioreactor-assisted in-cell NMR of nucleic acids and proteins, Journal of Biomolecular Nmr, (2023) 13, 10.1007/s10858-023-00422-7

B. Hleli, et al.: Closo-dodecaborate-based dianionic surfactants with distorted classical morphology: Synthesis and atypical micellization in water, J. Colloid Interface Sci., 648 (2023) 809-819, 10.1016/j.jcis.2023.06.013

P. Kolenko, et al.: Diffraction anisotropy and paired refinement: crystal structure of H33, a protein binder to interleukin 10, J. Appl. Crystallogr., 56 (2023) 1261-1266, 10.1107/s160057672300479x

F. Leesch, et al.: A molecular network of conserved factors keeps ribosomes dormant in the egg, Nature, 613 (2023) 712-+, 10.1038/s41586-022-05623-y

J. Petersen, et al.: A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology, Nature Communications, 14 (2023) 22, 10.1038/s41467-023-38663-7

T. Machackova, et al.: Utility of RNA sequencing for transcriptome analysis of small extracellular vesicles derived from blood sera of colorectal cancer patients, Cancer Res., 83 (2023) 3, 10.1158/1538-7445.Am2023-6709

P.N. Pham, et al.: Regulation of IL-24/IL-20R2 complex formation using photocaged tyrosines and UV light, Front. Mol. Biosci., 10 (2023) 14, 10.3389/fmolb.2023.1214235

P. Pourali, et al.: Biological Production of Gold Nanoparticles at Different Temperatures: Efficiency Assessment, Particle & Particle Systems Characterization, (2023) 10, 10.1002/ppsc.202200182

P. Slavik, et al.: Synthesis of Enantiomerically Pure Bambus 6 urils Utilizing Orthogonal Protection of Glycolurils, Journal of Organic Chemistry, (2023) 9, 10.1021/acs.joc.3c00667

J. Novotny, et al.: Flipping hosts in hyperfine fields of paramagnetic guests, Cell Rep. Phys. Sci., 4 (2023) 15, 10.1016/j.xcrp.2023.101461

M. Opatikova, et al.: Cryo-EM structure of a plant photosystem II supercomplex with light-harvesting protein Lhcb8 and & alpha;-tocopherol, Nat. Plants, (2023) 14, 10.1038/s41477-023-01483-0

H. Paternoga, et al.: Structural conservation of antibiotic interaction with ribosomes, Nat. Struct. Mol. Biol., (2023) 35, 10.1038/s41594-023-01047-y

T. Pokorny, et al.: Ethanol Dehydrogenation over Copper-Silica Catalysts: From Sub-Nanometer Clusters to 15 nm Large Particles, ACS Sustain. Chem. Eng., 11 (2023) 10980-10992, 10.1021/acssuschemeng.2c06777

S.K. Sah-Teli, et al.: Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial 8-oxidation trifunctional enzymes, Structure, 31 (2023) 812-+, 10.1016/j.str.2023.04.011

F. Silveri, et al.: Impedimetric immunosensor for microalbuminuria based on a WS2/Au water-phase assembled nanocomposite, Microchim. Acta, 190 (2023) 12, 10.1007/s00604-023-05873-1

D. Vondrasek, et al.: Microstructural Analysis of Collagenous Structures in Relapsed Clubfoot Tissue, Microsc. microanal., 29 (2023) 265-272, 10.1093/micmic/ozac012

M. Zapletalova, et al.: BABA-induced pathogen resistance: a multi-omics analysis of the tomato response reveals a hyper-receptive status involving ethylene, Hortic. Res.-England, 10 (2023) 14, 10.1093/hr/uhad068

P.J. Vermeire, et al.: Molecular structure of soluble vimentin tetramers, Sci Rep, 13 (2023) 16, 10.1038/s41598-023-34814-4

H. Sulzen, et al.: Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction, Nature Communications, 14 (2023) 18, 10.1038/s41467-023-37988-7

P. Pourali, et al.: Fate of the capping agent of biologically produced gold nanoparticles and adsorption of enzymes onto their surface, Sci Rep, 13 (2023) 12, 10.1038/s41598-023-31792-5

M. Nemergut, et al.: Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate, Molecular Neurodegeneration, 18 (2023) 25, 10.1186/s13024-023-00620-9

L. Motlova, et al.: Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6), ACS Chem. Biol., 18 (2023) 1594-1610, 10.1021/acschembio.3c00212

B. Hustakova, et al.: A highly active S1-P1 nuclease from the opportunistic pathogen Stenotrophomonas maltophilia cleaves c-di-GMP, Febs Letters, (2023) 16, 10.1002/1873-3468.14683

Z. Bytesnikova, et al.: New insight into the biocompatibility/toxicity of graphene oxides and their reduced forms on Chlamydomonas reinhardtii, NanoImpact, 31 (2023) 12, 10.1016/j.impact.2023.100468

M. Zalud, et al.: Detection of Single Ag Nanoparticles Using Laser Desorption/Ionization Mass Spectrometry, J. Am. Soc. Mass Spectrom., (2023) 8, 10.1021/jasms.3c00137

S.G. Ullattil, et al.: Light-Powered Self-Adaptive Mesostructured Microrobots for Simultaneous Microplastics Trapping and Fragmentation via in situ Surface Morphing, Small, (2023) 9, 10.1002/smll.202301467

D. Novakova, et al.: Pseudomonas petrae sp. nov. isolated from regolith samples in Antarctica, Syst. Appl. Microbiol., 46 (2023) 9, 10.1016/j.syapm.2023.126424

L. Leonova, et al.: Hydrophobicity Boosts Catalytic Activity: The Tailoring of Aluminosilicates with Trimethylsilyl Groups, ChemCatChem, (2023) 17, 10.1002/cctc.202300449

K. Hanelova, et al.: Autophagy modulators influence the content of important signalling molecules in PS-positive extracellular vesicles, Cell Commun. Signal., 21 (2023) 21, 10.1186/s12964-023-01126-z

V. Bukova, et al.: New findings on the action of hypericin in hypoxic cancer cells with a focus on the modulation of side population cells, Biomed. Pharmacother., 163 (2023) 15, 10.1016/j.biopha.2023.114829

J. Dvorak, et al.: The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips, Clin. Proteom., 20 (2023) 10, 10.1186/s12014-023-09410-3

J. Czubinsk, et al.: Characteristics of N-Glycosylation and Its Impact on the Molecular Behavior of Lupinus angustifolius ?-Conglutin, J. Agric. Food Chem., (2023) 11, 10.1021/acs.jafc.3c00727

K. Mrazova, et al.: Urany-Less Low Voltage Transmission Electron Microscopy: A Powerful Tool for Ultrastructural Studying of Cyanobacterial Cells, Microorganisms, 11 (2023) 13, 10.3390/microorganisms11040888

G. Pampararo, et al.: Ethanol dehydrogenation to acetaldehyde with mesoporous Cu-SiO2 catalysts prepared by aerosol-assisted sol-gel, Chem. Eng. J., 465 (2023) 13, 10.1016/j.cej.2023.142715

D. Hradsky, et al.: Catalytic performance of micro-mesoporous zirconosilicates prepared by non-hydrolytic sol-gel in ethanol-acetaldehyde conversion to butadiene and related reactions, Appl. Catal. A-Gen., 652 (2023) 13, 10.1016/j.apcata.2023.119037

Z. Razmara, et al.: Catalytic activity of a new Cd (II) complex in the peroxidation of cyclohexane and the resulting CdO nanoparticles in the removal of Congo red, Appl. Organomet. Chem., (2023) 16, 10.1002/aoc.7079

L. Janacova, et al.: Catechol-O-methyl transferase suppresses cell invasion and interplays with MET signaling in estrogen dependent breast cancer, Sci Rep, 13 (2023) 14, 10.1038/s41598-023-28078-1

P. Takacsova, et al.: A color-tunable single-benzene fluorophore-based sensor for sensitive detection of palladium in solution and living cells, Analyst, (2023) 6, 10.1039/d3an00046j

S. Hosseinpoor, et al.: Competing and directing interactions in new phosphoramide/thiophosphoramide structures: energy considerations and evidence for CHMIDLINE HORIZONTAL ELLIPSISHC contacts and aliphatic-aromatic stacking, Crystengcomm, (2023) 13, 10.1039/d3ce00204g

P. Lapcik, et al.: DiaPASEF proteotype analysis indicates changes in cell growth and metabolic switch induced by caspase-9 inhibition in chondrogenic cells, Proteomics, (2023) 14, 10.1002/pmic.202200408

T. Kouba, et al.: Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106, Cell Reports, 42 (2023) 24, 10.1016/j.celrep.2022.111901

K. Vrchovecka, et al.: Effect of titanium nanostructured surface on fibroblast behavior, J. Biomed. Mater. Res. Part A, (2023) 11, 10.1002/jbm.a.37531

B. Heames, et al.: Experimental characterization of de novo proteins and their unevolved random-sequence counterparts, Nat. Ecol. Evol., 7 (2023) 570-+, 10.1038/s41559-023-02010-2

V. Prysiazhnyi, et al.: Fate of Gold Nanoparticles in Laser Desorption/Ionization Mass Spectrometry: Toward the Imaging of Individual Nanoparticles, J. Am. Soc. Mass Spectrom., 34 (2023) 570-578, 10.1021/jasms.2c00300

J. Vavra, et al.: Characterization of the interaction between the tumour suppressor p53 and heme and its role in the protein conformational dynamics studied by various spectroscopic techniques and hydrogen/deuterium exchange coupled with mass spectrometry, J. Inorg. Biochem., 243 (2023) 14, 10.1016/j.jinorgbio.2023.112180

A. Mukherjee, et al.: An investigation on the multiple roles of CeO2 nanoparticle in electrochemical sensing: Biomimetic activity and electron acceptor, Journal of Electroanalytical Chemistry, 935 (2023) 11, 10.1016/j.jelechem.2023.117301

M. Genova, et al.: Tubulin polyglutamylation differentially regulates microtubule-interacting proteins, Embo J., (2023) 17, 10.15252/embj.2022112101

M. Huliciak, et al.: Combined in vitro and cell-based selection display method producing specific binders against IL-9 receptor in high yields, Febs Journal, (2023) 13, 10.1111/febs.16726

A.S. Chaudhari, et al.: Genetically encoded non-canonical amino acids reveal asynchronous dark reversion of chromophore, backbone, and side-chains in EL222, Protein Sci., 32 (2023) 22, 10.1002/pro.4590

M. Makarov, et al.: Early Selection of the Amino Acid Alphabet Was Adaptively Shaped by Biophysical Constraints of Foldability, Journal of the American Chemical Society, (2023) 10, 10.1021/jacs.2c12987

J.C. Brandmeier, et al.: Digital and Analog Detection of SARS-CoV-2 Nucleocapsid Protein via an Upconversion-Linked Immunosorbent Assay, Anal. Chem., (2023) 7, 10.1021/acs.analchem.2c05670

M. Buchtelova, et al.: Insight into peculiar adhesion of cells to plasma-chemically prepared multifunctional "amino-glue" surfaces, Plasma Processes and Polymers, (2023) 15, 10.1002/ppap.202200157

Z. Hasanova, et al.: Human senataxin is a bona fide R-loop resolving enzyme and transcription termination factor, Nucleic Acids Res., (2023) 20, 10.1093/nar/gkad092

J. Houser, et al.: The NFkB activation domain is 14-amino-acid-long variant of the 9aaTAD, Biochem. J., 480 (2023) 297-306, 10.1042/bcj20220605

J. Chyba, et al.: Nature of NMR Shifts in Paramagnetic Octahedral Ru(III) Complexes with Axial Pyridine-Based Ligands, Inorganic Chemistry, (2023) 14, 10.1021/acs.inorgchem.2c03282

T.O. Koller, et al.: The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition, Journal of the American Chemical Society, (2023) 13, 10.1021/jacs.2c08816

L. Kuntova, et al.: Staphylococcus aureus Prophage-Encoded Protein Causes Abortive Infection and Provides Population Immunity against Kayviruses, mBio, (2023) 15, 10.1128/mbio.02490-22

F. Leesch, et al.: A molecular network of conserved factors keeps ribosomes dormant in the egg, Nature, (2023) 28, 10.1038/s41586-022-05623-y

S. Legartova, et al.: Irradiation potentiates p53 phosphorylation and p53 binding to the promoter and coding region of the TP53 gene, Biochimie, 204 (2023) 154-168, 10.1016/j.biochi.2022.09.013

A. Makarov, et al.: The role of invariant surface glycoprotein 75 in xenobiotic acquisition by African trypanosomes, Microb. Cell, 10 (2023) 18-35, 10.15698/mic2023.02.790

H. Mazanec, et al.: Secretion of extracellular vesicles during ontogeny of the tapeworm Schistocephalus solidus, Folia Parasitol., 70 (2023) 8, 10.14411/fp.2023.003

K. Mitrevska, et al.: Chick chorioallantoic membrane (CAM) assay for the evaluation of the antitumor and antimetastatic activity of platinum-based drugs in association with the impact on the amino acid metabolism, Mater. Today Bio, 19 (2023) 14, 10.1016/j.mtbio.2023.100570

S. Tanasa, et al.: A complex role of Arabidopsis CDKD;3 in meiotic progression and cytokinesis, Plant Direct, 7 (2023) 16, 10.1002/pld3.477

P. Veverka, et al.: Electron microscopy reveals toroidal shape of master neuronal cell differentiator REST - RE1-silencing transcription factor, Comp. Struct. Biotechnol. J.. 21 (2023) 731-741, 10.1016/j.csbj.2022.12.026

A. Schenkmayerova, et al.: Catalytic mechanism for Renilla-type luciferases, Nat. Catal., (2023) 18, 10.1038/s41929-022-00895-z

H. Stepankova, et al.: Unveiling the nanotoxicological aspects of Se nanomaterials differing in size and morphology, Bioact. Mater., 20 (2023) 489-500, 10.1016/j.bioactmat.2022.06.014

Y. Liu, et al.: Sub-Millisecond Photoinduced Dynamics of Free and EL222-Bound FMN by Stimulated Raman and Visible Absorption SpectroscopiesBiomolecules, (2023) 13, 10.3390/biom13010161

2022

D. Zapletal, et al.: Structural and functional basis of mammalian microRNA biogenesis by Dicer, Molecular Cell, 82 (2022) 4064-+, 10.1016/j.molcel.2022.10.010

M. van der Verren, et al.: Airborne Preparation of Small Gold Nanoparticles Dispersed on Mesoporous Silica for the Catalytic Oxidation of Glycerol to Dihydroxyacetone, ACS Appl. Nano Mater., (2022) 9, 10.1021/acsanm.2c04786

P.M. Szczepanik, et al.: Convergent Assembly of the Tricyclic Labdane Core Enables Synthesis of Diverse Forskolin-like Molecules, Angewandte Chemie-International Edition, (2022) 8, 10.1002/anie.202213183

M. Stiborek, et al.: Infrared Laser Desorption of Intact Nanoparticles for Digital Tissue Imaging, Anal. Chem., (2022) 7, 10.1021/acs.analchem.2c05216

J. Rudolfova, et al.: Adamantane-Substituted Purine Nucleosides: Synthesis, Host-Guest Complexes with beta-Cyclodextrin and Biological Activity, International Journal of Molecular Sciences, 23 (2022) 22, 10.3390/ijms232315143

J.L. Pacheco-Garcia, et al.: Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme, Febs Journal, (2022) 19, 10.1111/febs.16677

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2021

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M. Sojka, et al.: Quantum chemical calculations of P-31 NMR chemical shifts of P-donor ligands in platinum(II) complexes, J. Mol. Model., 25 (2019) 8, 10.1007/s00894-019-4222-1 

M. Sojka, et al.: Bifurcated hydrogen bonds in platinum(II) complexes with phosphinoamine ligands, Polyhedron, 170 (2019) 593-601, 10.1016/j.poly.2019.06.014 

V. Sychrovsky, et al.: Ascorbigen A-NMR identification, Magnetic Resonance in Chemistry, (2019) 10.1002/mrc.4890 

B. Tesarova, et al.: Folic acid-mediated re-shuttling of ferritin receptor specificity towards a selective delivery of highly cytotoxic nickel(II) coordination compounds, Int. J. Biol. Macromol., 126 (2019) 1099-1111, 10.1016/j.ijbiomac.2018.12.128 

F. Trcka, et al.: Human Stress-inducible Hsp70 Has a High Propensity to Form ATP-dependent Antiparallel Dimers That Are Differentially Regulated by Cochaperone Binding, Mol. Cell. Proteomics, 18 (2019) 320-337, 10.1074/mcp.RA118.001044 

J. Treml, et al.: Antioxidant Activity of Selected Stilbenoid Derivatives in a Cellular Model System, Biomolecules, 9 (2019) 16, 10.3390/biom9090468 

L. Trnkova, et al.: Comparative Electrochemical and Spectroscopic Studies of I-motif-forming DNA Nonamers, Electroanalysis,  14, 10.1002/elan.201900323 

H. Valkenier, et al.: Fluorinated Bambusurils as Highly Effective and Selective Transmembrane Cl-/HCO3- Antiporters, Chem, 5 (2019) 429-444, 10.1016/j.chempr.2018.11.008 

P. Vankova, et al.: A Dynamic Core in Human NQO1 Controls the Functional and Stability Effects of Ligand Binding and Their Communication across the Enzyme Dimer, Biomolecules, 9 (2019) 17, 10.3390/biom9110728 

P. Veverka, et al.: Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point, International Journal of Molecular Sciences, 20 (2019) 13, 10.3390/ijms20133186 

J. Veznik, et al.: Elusive pK(a)' of aminoferrocene determined with voltammetric methods in buffered and unbuffered systems and practical aspects of such experiments, Electrochim. Acta, 318 (2019) 534-541, 10.1016/j.electacta.2019.05.113 

V. Vrbovska, et al.: Staphylococcus petrasii diagnostics and its pathogenic potential enhanced by mobile genetic elements, Int. J. Med. Microbiol., 309 (2019) 14, 10.1016/j.ijmm.2019.151355 

V. Vykoukal, et al.: Morphology Control in AgCu Nanoalloy Synthesis by Molecular Cu(I) Precursors, Inorganic Chemistry, 58 (2019) 15246-15254, 10.1021/acs.inorgchem.9b02172 

V. Vykoukal, et al.: Solvothermal hot injection synthesis of core-shell AgNi nanoparticles, J. Alloy. Compd., 770 (2019) 377-385, 10.1016/j.jallcom.2018.08.082 

J. Wald, et al.: Cryo-EM structure of pleconaril-resistant rhinovirus-B5 complexed to the antiviral OBR-5-340 reveals unexpected binding site, Proceedings of the National Academy of Sciences of the United States of America, 116 (2019) 19109-19115, 10.1073/pnas.1904732116 

J. Zahradník, et al.: Flexible regions govern promiscuous binding of IL-24 to receptors IL-20R1 and IL-22R1, Febs Journal, 286 (2019) 3858-3873, 10.1111/febs.14945 

J. Zeman, et al.: Binding of eIF3 in complex with eIF5 and eIF1 to the 40S ribosomal subunit is accompanied by dramatic structural changes, Nucleic Acids Res., 47 (2019) 8282-8300, 10.1093/nar/gkz570 

M. Zeman, et al.: New Genus Fibralongavirus in Siphoviridae Phages of Staphylococcus pseudintermedius, Viruses-Basel, 11 (2019) 17, 10.3390/v11121143 

2018

Acimovic, I. et al. Post-Translational Modifications and Diastolic Calcium Leak Associated to the Novel RyR2-D3638A Mutation Lead to CPVT in Patient-Specific hiPSC-Derived Cardiomyocytes. Journal of Clinical Medicine 7, 22, doi:10.3390/jcm7110423 (2018).

Bartova, E. et al. Irradiation by gamma-rays reduces the level of H3S10 phosphorylation and weakens the G2 phase-dependent interaction between H3S10 phosphorylation and gamma H2AX. Biochimie 154, 86-98, doi:10.1016/j.biochi.2018.07.029 (2018).

Bartova, V. et al. Proteomic characterization and antifungal activity of potato tuber proteins isolated from starch production waste under different temperature regimes. Applied Microbiology and Biotechnology 102, 10551-10560, doi:10.1007/s00253-018-9373-y (2018).

Benesik, M. et al. Role of SH3b binding domain in a natural deletion mutant of Kayvirus endolysin LysF1 with a broad range of lytic activity. Virus Genes 54, 130-139, doi:10.1007/s11262-017-1507-2 (2018).

Caluori, G. et al. Advanced and Rationalized Atomic Force Microscopy Analysis Unveils Specific Properties of Controlled Cell Mechanics. Frontiers in Physiology 9, 11, doi:10.3389/fphys.2018.01121 (2018).

Chyba, J., Novak, M., Munzarova, P., Novotny, J. & Marek, R. Through-Space Paramagnetic NMR Effects in Host-Guest Complexes: Potential Ruthenium(III) Metallodrugs with Macrocyclic Carriers. Inorganic Chemistry 57, 8735-8747, doi:10.1021/acs.inorgchem.7b03233 (2018).

Crowe-McAuliffe, C. et al. Structural basis for antibiotic resistance mediated by the Bacillus subtilis ABCF ATPase VmlR. Proceedings of the National Academy of Sciences of the United States of America 115, 8978-8983, doi:10.1073/pnas.1808535115 (2018).

Darebna, P. et al. Detection and Quantification of Carbohydrate-Deficient Transferrin by MALDI-Compatible Protein Chips Prepared by Ambient Ion Soft Landing. Clinical Chemistry 64, 1319-1326, doi:10.1373/clinchem.2017.285452 (2018).

Doroshenko, I. et al. New molecular heptanuclear cobalt phosphonates: synthesis, structures and magnetic properties. New Journal of Chemistry 42, 9568-9577, doi:10.1039/c8nj00902c (2018).

Doroshenko, I. et al. Hexanuclear iron(III) alpha-aminophosphonate: synthesis, structure, and magnetic properties of a molecular wheel. New Journal of Chemistry 42, 1931-1938, doi:10.1039/c7nj03606j (2018).

Dostalova, S. et al. Prostate-Specific Membrane Antigen-Targeted Site-Directed Antibody-Conjugated Apoferritin Nanovehicle Favorably Influences In Vivo Side Effects of Doxorubicin. Scientific Reports 8, 13, doi:10.1038/s41598-018-26772-z (2018).

Dzatko, S. et al. Evaluation of the Stability of DNA i-Motifs in the Nuclei of Living Mammalian Cells. Angewandte Chemie-International Edition 57, 2165-2169, doi:10.1002/anie.201712284 (2018).

Evangelidis, T. et al. Automated NMR resonance assignments and structure determination using a minimal set of 4D spectra. Nature Communications 9, 13, doi:10.1038/s41467-017-02592-z (2018).

Farka, Z. et al. Prussian Blue Nanoparticles as a Catalytic Label in a Sandwich Nanozyme-Linked Immunosorbent Assay. Analytical Chemistry 90, 2348-2354, doi:10.1021/acs.analchem.7b04883 (2018).

Fiala, T., Sleziakova, K., Marsalek, K., Salvadori, K. & Sindelar, V. Thermodynamics of Halide Binding to a Neutral Bambusuril in Water and Organic Solvents. Journal of Organic Chemistry 83, 1903-1912, doi:10.1021/acs.joc.7b02846 (2018).

Fuzik, T. et al. Structure of tick-borne encephalitis virus and its neutralization by a monoclonal antibody. Nature Communications 9, 11, doi:10.1038/s41467-018-02882-0 (2018).

Garlikova, Z. et al. Generation of a Close-to-Native In Vitro System to Study Lung Cells-Extracellular Matrix Crosstalk. Tissue Engineering Part C-Methods 24, 1-13, doi:10.1089/ten.tec.2017.0283 (2018).

Golan, M. et al. Cryopreserved Cells Regeneration Monitored by Atomic Force Microscopy and Correlated With State of Cytoskeleton and Nuclear Membrane. Ieee Transactions on Nanobioscience 17, 485-497, doi:10.1109/tnb.2018.2873425 (2018).

Graf, M. et al. Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nature Communications 9, 11, doi:10.1038/s41467-018-05465-1 (2018).

Grillova, L. et al. Sequencing of Treponema pallidum subsp pallidum from isolate UZ1974 using Anti-Treponemal Antibodies Enrichment: First complete whole genome sequence obtained directly from human clinical material. Plos One 13, 14, doi:10.1371/journal.pone.0202619 (2018).

Hanakova, K. et al. SEMIQUANTITATIVE ASSESSMENT OF DISHEVELLED-3 PHOSPHORYLATION STATUS BY MASS SPECTROMETRY. Hungarian Journal of Industry and Chemistry 46, 3-6, doi:10.1515/hjic-2018-0002 (2018).

Haniewicz, P. et al. Molecular Mechanisms of Photoadaptation of Photosystem I Supercomplex from an Evolutionary Cyanobacterial/Algal Intermediate. Plant Physiology 176, 1433-1451, doi:10.1104/pp.17.01022 (2018).

Havel, S., Khirsariya, P., Akavaram, N., Paruch, K. & Carbain, B. Preparation of 3,4-Substituted-5-Aminopyrazoles and 4-Substituted-2-Aminothiazoles. Journal of Organic Chemistry 83, 15380-15405, doi:10.1021/acs.joc.8b02655 (2018).

Havel, V., Sadilova, T. & Sindelar, V. Unsubstituted Bambusurils: Post-Macrocyclization Modification of Versatile Intermediates. Acs Omega 3, 4657-4663, doi:10.1021/acsomega.8b00497 (2018).

Hegemann, D. et al. Stable, nanometer-thick oxygen-containing plasma polymer films suited for enhanced biosensing. Plasma Processes and Polymers 15, 9, doi:10.1002/ppap.201800090 (2018).

Hernychova, L. et al. The C-type lectin-like receptor Nkrp1b: structural features affecting protein conformation and interactions. Febs Open Bio 8, 418-418 (2018).

Jancarikova, G. et al. Synthesis of alpha-L-Fucopyranoside-Presenting Glycoclusters and Investigation of Their Interaction with Photorhabdus asymbiotica Lectin (PHL). Chemistry-a European Journal 24, 4055-4068, doi:10.1002/chem.201705853 (2018).

Jandova, Z., Trosanova, Z., Weisova, V., Oostenbrink, C. & Hritz, J. Free energy calculations on the stability of the 14-3-3 zeta protein. Biochimica Et Biophysica Acta-Proteins and Proteomics 1866, 442-450, doi:10.1016/j.bbapap.2017.11.012 (2018).

Jeremias, L., Novotny, J., Repisky, M., Komorovsky, S. & Marek, R. Interplay of Through-Bond Hyperfine and Substituent Effects on the NMR Chemical Shifts in Ru(III) Complexes. Inorganic Chemistry 57, 8748-8759, doi:10.1021/acs.inorgchem.8b00073 (2018).

Jurnecka, D., Man, P., Sebo, P. & Bumba, L. Bordetella pertussis and Bordetella bronchiseptica filamentous hemagglutinins are processed at different sites. Febs Open Bio 8, 1256-1266, doi:10.1002/2211-5463.12474 (2018).

Kasakova, M. et al. Selectivity of original C-hexopyranosyl calix 4 arene conjugates towards lectins of different origin. Carbohydrate Research 469, 60-72, doi:10.1016/j.carres.2018.08.012 (2018).

Kaurov, I. et al. The Diverged Trypanosome MICOS Complex as a Hub for Mitochondrial Cristae Shaping and Protein Import. Current Biology 28, 3393-+, doi:10.1016/j.cub.2018.09.008 (2018).

Kolenko, P. et al. Ligands in the active site of carbohydrate oxidase from Microdochium nivale. Febs Open Bio 8, 181-181 (2018).

Kollhammerova, I. et al. Alumazene Reactivity with Quinolinols - Addition and Substitution Reactions on the Al3N3 Ring. Acta Chimica Slovenica 65, 955-963, doi:10.17344/acsi.2018.4624 (2018).

Komarek, J. et al. Structure and properties of AB21, a novel Agaricus bisporus protein with structural relation to bacterial pore-forming toxins. Proteins-Structure Function and Bioinformatics 86, 897-911, doi:10.1002/prot.25522 (2018).

Koval, T. & Dohnalek, J. Characteristics and application of S1-P1 nucleases in biotechnology and medicine. Biotechnology Advances 36, 603-612, doi:10.1016/j.biotechadv.2017.12.007 (2018).

Kylarova, S., Psenakova, K., Herman, P., Obsilova, V. & Obsil, T. CaMKK2 kinase domain interacts with the autoinhibitory region through the N-terminal lobe including the RP insert. Biochimica Et Biophysica Acta-General Subjects 1862, 2304-2313, doi:10.1016/j.bbagen.2018.07.025 (2018).

Lacina, K. et al. Graphene Oxide from Improved Hummers' Method: Is This Material Suitable for Reproducible Electrochemical (Bio)Sensing? Ecs Journal of Solid State Science and Technology 7, M166-M171, doi:10.1149/2.0171810jss (2018).

Liskova, R., Slavata, L., Cerny, J., Valis, K. & Novak, P. Interaction of transcription factor TEAD1 with its DNA response elements originating from human genes. Febs Open Bio 8, 94-95 (2018).

Makhneva, E., Farka, Z., Skladal, P. & Zajickova, L. Cyclopropylamine plasma polymer surfaces for label-free SPR and QCM immunosensing of Salmonella. Sensors and Actuators B-Chemical 276, 447-455, doi:10.1016/j.snb.2018.08.055 (2018).

Maslanova, I. et al. Description and Comparative Genomics of Macrococcus caseolyticus subsp hominis subsp nov., Macrococcus goetzii sp nov., Macrococcus epidermidis sp nov., and Macrococcus bohemicus sp nov., Novel Macrococci From Human Clinical Material With Virulence Potential and Suspected Uptake of Foreign DNA by Natural Transformation. Frontiers in Microbiology 9, 22, doi:10.3389/fmicb.2018.01178 (2018).

Melkova, K. et al. Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics. Journal of Biological Chemistry 293, 13297-13309, doi:10.1074/jbc.RA118.001769 (2018).

Modlitbova, P. et al. Time-Dependent Growth of Silica Shells on CdTe Quantum Dots. Nanomaterials 8, 9, doi:10.3390/nano8060439 (2018).

Modlitbova, P. et al. Comparative investigation of toxicity and bioaccumulation of Cd-based quantum dots and Cd salt in freshwater plant Lemna minor L. Ecotoxicology and Environmental Safety 147, 334-341, doi:10.1016/j.ecoenv.2017.08.053 (2018). 

Modlitbova, P. et al. Short-term assessment of cadmium toxicity and uptake from different types of Cd-based Quantum Dots in the model plant Allium cepa L. Ecotoxicology and Environmental Safety 153, 23-31, doi:10.1016/j.ecoenv.2018.01.044 (2018).

Moulick, A. et al. Real-Time Visualization of Cell Membrane Damage Using Gadolinium Schiff Base Complex-Doped Quantum Dots. Acs Applied Materials & Interfaces 10, 35859-35868, doi:10.1021/acsami.8b15868 (2018).

Munster, L. et al. Dialdehyde cellulose crosslinked poly(vinyl alcohol) hydrogels: Influence of catalyst and crosslinker shelf life. Carbohydrate Polymers 198, 181-190, doi:10.1016/j.carbpol.2018.06.035 (2018).

Nakajima, R. et al. 2-Aminoadipic Acid-C(O)-Glutamate Based Prostate-Specific Membrane Antigen Ligands for Potential Use as Theranostics. Acs Medicinal Chemistry Letters 9, 1099-1104, doi:10.1021/acsmedchemlett.8b00318 (2018).

Nevidalova, H., Michalcova, L. & Glatz, Z. In-depth insight into the methods of plasma protein-drug interaction studies: Comparison of capillary electrophoresis-frontal analysis, isothermal titration calorimetry, circular dichroism and equilibrium dialysis. Electrophoresis 39, 581-589, doi:10.1002/elps.201700325 (2018).

Novak, P., Darebna, P. & Pompach, P. A novel generation of protein chips for clinical diagnostics. Febs Open Bio 8, 42-42 (2018).

Novotny, J. et al. Hyperfine Effects in Ligand NMR: Paramagnetic Ru(III) Complexes with 3 Substituted Pyridines. Inorganic Chemistry 57, 641-652, doi:10.1021/acs.inorgchem.7b02440 (2018).

Ostatna, V., Kasalova, V., Kmetova, K. & Sedo, O. Changes of electrocatalytic response of bovine serum albumin after its methylation and acetylation. Journal of Electroanalytical Chemistry 821, 97-103, doi:10.1016/j.jelechem.2017.11.044 (2018).

Pekar, S. et al. Venom gland size and venom complexity-essential trophic adaptations of venomous predators: A case study using spiders. Molecular Ecology 27, 4257-4269, doi:10.1111/mec.14859 (2018).

Podhorsky, J. et al. Preparation of Heteroleptic Tin(IV) N,O-beta-Heteroarylalkenolate Complexes and Their Properties as PI-MOCVD Precursors for SnO2 Deposition. European Journal of Inorganic Chemistry, 5027-5035, doi:10.1002/ejic.201800913 (2018).

Podzimek, T. et al. N-glycosylation of tomato nuclease TBN1 produced in N. benthamiana and its effect on the enzyme activity. Plant Science 276, 152-161, doi:10.1016/j.plantsci.2018.08.011 (2018).

Prochazkova, M. et al. Virion structure and genome delivery mechanism of sacbrood honeybee virus. Proceedings of the National Academy of Sciences of the United States of America 115, 7759-7764, doi:10.1073/pnas.1722018115 (2018).

Psenakova, K. et al. 14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2). Biochimica Et Biophysica Acta-General Subjects 1862, 1612-1625, doi:10.1016/j.bbagen.2018.04.006 (2018).

Ptacek, J. et al. The calcium-binding site of human glutamate carboxypeptidase II is critical for dimerization, thermal stability, and enzymatic activity. Protein Sci. 27, 1575-1584, doi:10.1002/pro.3460 (2018).

Roudnicky, P. et al. Identification and partial characterization of a novel serpin from Eudiplozoon nipponicum (Monogenea, Polyopisthocotylea). Parasite 25, 13, doi:10.1051/parasite/2018062 (2018).

Rovnanik, P., Rovnanikova, P., Vysvaril, M., Grzeszczyk, S. & Janowska-Renkas, E. Rheological properties and microstructure of binary waste red brick powder/metakaolin geopolymer. Construction and Building Materials 188, 924-933, doi:10.1016/j.conbuildmat.2018.08.150 (2018).

Rozbesky, D. et al. Impact of Chemical Cross-Linking on Protein Structure and Function. Analytical Chemistry 90, 1104-1113, doi:10.1021/acs.analchem.7b02863 (2018).

Sedo, O., Radolfova-Krizova, L., Nemec, A. & Zdrahal, Z. Limitations of routine MALDI-TOF mass spectrometric identification of Acinetobacter species and remedial actions. Journal of Microbiological Methods 154, 79-85, doi:10.1016/j.mimet.2018.10.009 (2018).

Sharma, S. et al. Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation. Proceedings of the National Academy of Sciences of the United States of America 115, E7053-E7062, doi:10.1073/pnas.1803909115 (2018).

Sicorello, A. et al. The Structural Properties in Solution of the Intrinsically Mixed Folded Protein Ataxin-3. Biophysical Journal 115, 59-71, doi:10.1016/j.bpj.2018.05.029 (2018).

Skerlova, J. et al. Crystal structure of native beta-N-acetylhexosaminidase isolated from Aspergillus oryzae sheds light onto its substrate specificity, high stability, and regulation by propeptide. Febs Journal 285, 580-598, doi:10.1111/febs.14360 (2018).

Slavata, L., Kadek, A., Chmelik, J., Liskova, R. & Novak, P. Protein-nucleic acid complexes: insight into their gas-phase stability. Febs Open Bio 8, 422-422 (2018).

Smidova, A. et al. 14-3-3 protein masks the nuclear localization sequence of caspase-2. Febs Journal 285, 4196-4213, doi:10.1111/febs.14670 (2018).

Sokolov, J. & Sindelar, V. Chiral Bambusurils for Enantioselective Recognition of Carboxylate Anion Guests. Chemistry-a European Journal 24, 15482-15485, doi:10.1002/chem.201802748 (2018).

Spackova, N. et al. Protein environment affects the water-tryptophan binding mode. MD, QM/MM, and NMR studies of engrailed homeodomain mutants. Physical Chemistry Chemical Physics 20, 12664-12677, doi:10.1039/c7cp08623g (2018).

Stafkova, J. et al. Dynamic secretome of Trichomonas vaginalis: Case study of beta-amylasesMolecular & Cellular Proteomics 17, 304-320, doi:10.1074/mcp.RA117.000434 (2018).

Strouhal, M. et al. Complete genome sequences of two strains of Treponema pallidum subsp pertenue from Indonesia: Modular structure of several treponemal genes. Plos Neglected Tropical Diseases 12, 20, doi:10.1371/journal.pntd.0006867 (2018).

Stverakova, D. et al. Rapid Identification of Intact Staphylococcal Bacteriophages Using Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry. Viruses-Basel 10, 19, doi:10.3390/v10040176 (2018).

Taveri, G., Grasso, S., Gucci, F., Tousek, J. & Dlouhy, I. Bio-Inspired Hydro-Pressure Consolidation of Silica. Advanced Functional Materials 28, 8, doi:10.1002/adfm.201805794 (2018).

Trundova, M. et al. Highly stable single-strand-specific 3'-nuclease/nucleotidase from Legionella pneumophila. International Journal of Biological Macromolecules 114, 776-787, doi:10.1016/j.ijbiomac2018.03.113 (2018).

Vankova, P. et al. Regulation of chaperone - co-chaperone interaction by 14-3-3 proteins. Febs Open Bio 8, 419-419 (2018).

Vojackova, P., Chalupa, D., Prieboj, J., Necas, M. & Svenda, J. Enantioselective Conjugate Additions of 2-Alkoxycarbonyl-3(2H)-furanones. Organic Letters 20, 7085-7089, doi:10.1021/acs.orglett.8b03039 (2018).

Yawer, M. A., Sleziakova, K., Pavlovec, L. & Sindelar, V. Bambusurils. Bearing Nitro Groups and Their Further Modifications. European Journal of Organic Chemistry, 41-47, doi:10.1002/ejoc.201701329 (2018).

Zahonova, K. et al. Extensive molecular tinkering in the evolution of the membrane attachment mode of the Rheb GTPase. Scientific Reports 8, 11, doi:10.1038/s41598-018-23575-0 (2018).

Zahradnik, J., Kolarova, L., Parizkova, H., Kolenko, P. & Schneider, B. Interferons type II and their receptors R1 and R2 in fish species: Evolution, structure, and function. Fish & Shellfish Immunology 79, 140-152, doi:10.1016/j.fsi.2018.05.008 (2018).

2017

Bhat, S. S., Revankar, V. K., Khan, A., Pinjari, R. V. & Necas, M. Luminescent Ruthenium(II) Polypyridyl Complexes as Nonviral Carriers for DNA Delivery. Chemistry-an Asian Journal 12, 254-264, doi:10.1002/asia.201601515 (2017).

Blaha, J. et al. High-level expression and purification of soluble form of human natural killer cell receptor NKR-P1 in HEK293S GnTI(-) cells. Protein Expression and Purification 140, 36-43, doi:10.1016/j.pep.2017.07.016 (2017).

Bocanek, O., Sedo, O., Pekar, S. & Zdrahal, Z. Evaluation of sample preparation protocols for spider venom profiling by MALDI-TOF MS. Toxicon 133, 18-25, doi:10.1016/j.toxicon.2017.04.008 (2017).

Brabencova, S. et al. Variations of Histone Modification Patterns: Contributions of Inter-plant Variability and Technical Factors. Frontiers in Plant Science 8, 12, doi:10.3389/fpls.2017.02084 (2017).

Buchtelova, H. et al. pH-Responsive Hybrid Organic-Inorganic Ruthenium Nanoparticles for Controlled Release of Doxorubicin. Particle & Particle Systems Characterization 34, 9, doi:10.1002/ppsc.201700289 (2017).

Buchtelova, H. et al. Size-related cytotoxicological aspects of polyvinylpyrrolidone-capped platinum nanoparticles. Food Chem. Toxicol. 105, 337-346, doi:10.1016/j.fct.2017.04.043 (2017).

Chalupa, D. et al. Enantioselective Synthesis of Cephalimysins B and C. Organic Letters 19, 750-753, doi:10.1021/acs.orglett.6b03373 (2017).

Chamradova, I. et al. The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer. Colloid and Polymer Science 295, 107-115, doi:10.1007/s00396-016-3983-7 (2017).

Csavas, M. et al. Tri- and tetravalent mannoclusters cross-link and aggregate BC2L-A lectin from Burkholderia cenocepaciaCarbohydrate Research 437, 1-8, doi:10.1016/j.carres.2016.11.008 (2017).

Dostalova, S. et al. Apoferritin as an ubiquitous nanocarrier with excellent shelf life. International Journal of Nanomedicine 12, 2265-2278, doi:10.2147/ijn.s130267 (2017).

Farka, Z., Mickert, M. J., Hlavacek, A., Skladal, P. & Gorris, H. H. Single Molecule Upconversion-Linked Immunosorbent Assay with Extended Dynamic Range for the Sensitive Detection of Diagnostic Biomarkers. Analytical Chemistry 89, 11825-11830, doi:10.1021/acs.analchem.7b03542 (2017).

Fiala, T. et al. Bambusuril as a One-Electron Donor for Photoinduced Electron Transfer to Methyl Viologen in Mixed Crystals. Journal of the American Chemical Society 139, 2597-2603, doi:10.1021/jacs.6b08589 (2017).

Gajarsky, M. et al. Structure of a Stable G-Hairpin. Journal of the American Chemical Society 139, 3591-3594, doi:10.1021/jacs.6b10786 (2017).

Graf, M. et al. Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions. Nucleic Acids Research 45, 2887-2896, doi:10.1093/nar/gkw1272 (2017).

Grochalova, M. et al. Deep coverage of the beer proteome. Journal of Proteomics 162, 119-124, doi:10.1016/j.jprot.2017.05.001 (2017).

Hamzehee, F., Pourayoubi, M., Necas, M. & Choquesillo-Lazarte, D. Extensive analysis of N-H center dot center dot center dot O hydrogen bonding in four classes of phosphorus compounds: a combined experimental and database study. Acta Crystallographica Section C-Structural Chemistry 73, 287-+, doi:10.1107/s2053229617001516 (2017).

Havel, V., Babiak, M. & Sindelar, V. Modulation of Bambusuril Anion Affinity in Water. Chemistry-a European Journal 23, 8963-8968, doi:10.1002/chem.201701316 (2017).

Hlavacek, A. et al. Rapid single-step upconversion-linked immunosorbent assay for diclofenac. Microchimica Acta 184, 4159-4165, doi:10.1007/s00604-017-2456-0 (2017).

Huter, P. et al. Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P. Molecular Cell 68, 515-+, doi:10.1016/j.molcel.2017.10.014 (2017).

Hylse, O. et al. A Concise Synthesis of Forskolin. Angewandte Chemie-International Edition 56, 12586-12589, doi:10.1002/anie.201706809 (2017).

Ilgova, J. et al. A novel type I cystatin of parasite origin with atypical legumain-binding domain. Scientific Reports 7, 12, doi:10.1038/s41598-017-17598-2 (2017).

Jancarikova, G. et al. Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity. Plos Pathogens 13, 28, doi:10.1371/journal.ppat.1006564 (2017).

Jansen, S. et al. Quantitative mapping of microtubule-associated protein 2c (MAP2c) phosphorylation and regulatory protein 14-3-3 zeta-binding sites reveals key differences between MAP2c and its homolog Tau. Journal of Biological Chemistry 292, 6715-6727, doi:10.1074/jbc.M116.771097 (2017).

Jasnovidova, O. et al. Structure and dynamics of the RNAPII CTDsome with Rtt103. Proceedings of the National Academy of Sciences of the United States of America 114, 11133-11138, doi: doi:10.1073/pnas.1712450114

Jasnovidova, O., Krejcikova, M., Kubicek, K. & Stefl, R. Structural insight into recognition of phosphorylated threonine-4 of RNA polymerase II C-terminal domain by Rtt103p. Embo Reports 18, 906-913, doi:10.15252/embr.201643723 (2017).

Jelinkova, K. et al. Cubane Arrives on the Cucurbituril SceneOrganic Letters 19, 2698-2701, doi:10.1021/acs.orglett.7b01029 (2017).

Kacirova, M., Novacek, J., Man, P., Obsilova, V. & Obsil, T. Structural Basis for the 14-3-3 Protein-Dependent Inhibition of Phosducin Function. Biophysical Journal 112, 1339-1349, doi:10.1016/j.bpj.2017.02.036 (2017).

Kalabova, D. et al. Human procaspase-2 phosphorylation at both S139 and S164 is required for 14-3-3 binding. Biochemical and Biophysical Research Communications 493, 940-945, doi:10.1016/j.bbrc.2017.09.116 (2017).

Kalynych, S., Fuzik, T., Pridal, A., de Miranda, J. & Plevka, P. Cryo-EM study of slow bee paralysis virus at low pH reveals iflavirus genome release mechanism. Proceedings of the National Academy of Sciences of the United States of America 114, 598-603, doi:10.1073/pnas.1616562114 (2017).

Kejik, M., Moravec, Z., Barnes, C. E. & Pinkas, J. Hybrid microporous and mesoporous organosilicate covalent polymers with high porosity. Microporous Mesoporous Mat. 240, 205-215, doi:10.1016/j.micromeso.2016.11.012 (2017).

Kodedova, M. & Sychrova, H. Synthetic antimicrobial peptides of the halictines family disturb the membrane integrity of Candida cells. Biochimica Et Biophysica Acta-Biomembranes 1859, 1851-1858, doi:10.1016/j.bbamem.2017.06.005 (2017).

Kovalenko, A. et al. Adamantane substitutions: a path to high-performing, soluble, versatile and sustainable organic semiconducting materials. Journal of Materials Chemistry C 5, 4716-4723, doi:10.1039/c6tc05076j (2017).

Lousa, P., Nedozralova, H., Zupa, E., Novacek, J. & Hritz, J. Phosphorylation of the regulatory domain of human tyrosine hydroxylase 1 monitored using non-uniformly sampled NMR. Biophysical Chemistry 223, 25-29, doi:10.1016/j.bpc.2017.01.003 (2017).

Maier, L. et al. Diastereoselective Flexible Synthesis of Carbocyclic C-Nucleosides. Journal of Organic Chemistry 82, 3382-3402, doi:10.1021/acs.joc.6b02594 (2017).

Malatinsky, T. et al. Reversal of Stereoselectivity in Cycloadditions of Five-Membered Cyclic Nitrones Derived from Hexoses. European Journal of Organic Chemistry, 1086-1098, doi:10.1002/ejoc.201601488 (2017).

Mullapudi, E., Fuzik, T., Pridal, A. & Plevka, P. Cryo-electron Microscopy Study of the Genome Release of the Dicistrovirus Israeli Acute Bee Paralysis Virus. Journal of Virology 91, 12, doi:10.1128/jvi.02060-16 (2017).

Nardone, G. et al. YAP regulates cell mechanics by controlling focal adhesion assembly. Nature Communications 8, 13, doi:10.1038/ncomms15321 (2017).

Nejdl, L. et al. Platinum nanoparticles induce damage to DNA and inhibit DNA replicationPlos One 12, 19, doi:10.1371/journal.pone.0180798 (2017).

Nemec, A., Radolfova-Krizova, L., Maixnerova, M. & Sedo, O. Acinetobacter colistiniresistens sp nov (formerly genomic species 13 sensu Bouvet and Jeanjean and genomic species 14 sensu Tjernberg and Ursing), isolated from human infections and characterized by intrinsic resistance to polymyxins. International Journal of Systematic and Evolutionary Microbiology 67, 2134-2141, doi:10.1099/ijsem.0.001903 (2017).

Otevrel, J. & Bobal, P. Diamine-Tethered Bis(thiourea) Organocatalyst for Asymmetric Henry ReactionJournal of Organic Chemistry 82, 8342-8358, doi:10.1021/acs.joc.7b00079 (2017).

Otrusinova, O. et al. Conformational dynamics are a key factor in signaling mediated by the receiver domain of a sensor histidine kinase from Arabidopsis thaliana. Journal of Biological Chemistry 292, 17525-17540, doi:10.1074/jbc.M117.790212 (2017).

Pekarik, V. et al. Visualization of stable ferritin complexes with palladium, rhodium and iridium nanoparticles detected by their catalytic activity in native polyacrylamide gels. Dalton Transactions 46, 13690-13694, doi:10.1039/c7dt02818k (2017).

Prochazkova, I. et al. Targeted proteomics driven verification of biomarker candidates associated with breast cancer aggressiveness. Biochimica Et Biophysica Acta-Proteins and Proteomics 1865, 488-498, doi:10.1016/j.bbapap.2017.02.012 (2017).

Rais, R. et al. Discovery of a para-Acetoxy-benzyl Ester Prodrug of a Hydroxamate-Based Glutamate Carboxypeptidase II Inhibitor as Oral Therapy for Neuropathic Pain. Journal of Medicinal Chemistry 60, 7799-7809, doi:10.1021/acs.jmedchem.7b00825 (2017).

Rivera-Calzada, A. et al. The Structure of the R2TP Complex Defines a Platform for Recruiting Diverse Client Proteins to the HSP90 Molecular Chaperone SystemStructure 25, 1145-+, doi:10.1016/j.str.2017.05.016 (2017).

Salasova, A. et al. A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway. Molecular Neurodegeneration 12, 19, doi:10.1186/s13024-017-0193-9 (2017).

Schmidt, J. M. et al. A New Two-Step Chromatographic Procedure for Fractionation of Potato Proteins with Potato Fruit Juice and Spray-Dried Protein as Source Materials. Food and Bioprocess Technology 10, 1946-1958, doi:10.1007/s11947-017-1966-4 (2017).

Skubnik, K. et al. Structure of deformed wing virus, a major honey bee pathogen. Proceedings of the National Academy of Sciences of the United States of America 114, 3210-3215, doi:10.1073/pnas.1615695114 (2017).

Slany, M., Oppelt, J. & Cincarova, L. Formation of Staphylococcus aureus Biofilm in the Presence of Sublethal Concentrations of Disinfectants Studied via a Transcriptomic Analysis Using Transcriptome Sequencing (RNA-seq). Applied and Environmental Microbiology 83, 13, doi:10.1128/aem.01643-17 (2017).

Spurny, R. et al. Virion Structure of Black Queen Cell Virus, a Common Honeybee Pathogen. Journal of Virology 91, 14, doi:10.1128/jvi.02100-16 (2017).

Srb, P. et al. Triple resonance NMR relaxation experiments for studies of intrinsically disordered proteins. Journal of Biomolecular Nmr 69, 133-146, doi:10.1007/s10858-017-0138-1 (2017).

Stranava, M. et al. Coordination and redox state-dependent structural changes of the heme-based oxygen sensor AfGcHK associated with intraprotein signal transduction. Journal of Biological Chemistry 292, 20921-20935, doi:10.1074/jbc.M117.817023 (2017).

Styskalik, A., Babiak, M., Machac, P., Relichova, B. & Pinkas, J. New Adamantane-like Silicophosphate Cage and Its Reactivity toward Tris(pentafluorophenyl)borane. Inorganic Chemistry 56, 10699-10705, doi:10.1021/acs.inorgchem.7b01572 (2017).

Torti, E. et al. Supramolecular Storage and Controlled Photorelease of an Oxidizing Agent using a Bambusuril Macrocycle. Chemistry-a European Journal 23, 16768-16772, doi:10.1002/chem.201704948 

Uhlikova, H. et al. MAMP (microbe-associated molecular pattern)-induced changes in plasma membrane-associated proteins. Journal of Plant Physiology 210, 51-57, doi:10.1016/j.jplph.2016.12.005 (2017).

Weimann, I., Feller, J. & Zak, Z. Phase Equilibria in the System CuO-NiO-P4O10 and Synthesis, Crystal Structure, and Characterization of the New Copper Nickel Oxide Phosphate Cu3NiO(PO4)(2)Zeitschrift Fur Anorganische Und Allgemeine Chemie 643, 299-305, doi:10.1002/zaac.201600403 (2017).

Zachrdla, M. et al. Solution structure of domain 1.1 of the sigma(A) factor from Bacillus subtilis is preformed for binding to the RNA polymerase coreJournal of Biological Chemistry 292, 11610-11617, doi:10.1074/jbc.M117.784074 (2017).

Zadorozhny, K. et al. Fanconi-Anemia-Associated Mutations Destabilize RAD51 Filaments and Impair Replication Fork Protection. Cell Reports 21, 333-340, doi:10.1016/j.celrep.2017.09.062 (2017).

Zeman, M. et al. Staphylococcus sciuri bacteriophages double-convert for staphylokinase and phospholipase, mediate interspecies plasmid transduction, and package mecA geneScientific Reports 7, 11, doi:10.1038/srep46319 (2017

 

2016

Costanzo, G. et al. Non-Enzymatic Oligomerization of 3 ', 5 ' Cyclic AMP. Plos One 11, 14, doi:10.1371/journal.pone.0165723 (2016).

Cunderlova, V. et al. Catalytic nanocrystalline coordination polymers as an efficient peroxidase mimic for labeling and optical immunoassays. Microchim. Acta 183, 651-658, doi:10.1007/s00604-015-1697-z (2016).

Hafidh, S. et al. Quantitative proteomics of the tobacco pollen tube secretome identifies novel pollen tube guidance proteins important for fertilization. Genome Biology 17, 29, doi:10.1186/s13059-016-0928-x (2016).

Hlavacek, A. et al. Competitive Upconversion-Linked Immunosorbent Assay for the Sensitive Detection of Diclofenac. Anal. Chem. 88, 6011-6017, doi:10.1021/acs.analchem.6b01083 (2016).

Kalynych, S. et al. Virion Structure of Iflavirus Slow Bee Paralysis Virus at 2.6-Angstrom Resolution. Journal of Virology 90, 7444-7455, doi:10.1128/jvi.00680-16 (2016).

Koval, T. et al. Structural and Catalytic Properties of S1 Nuclease from Aspergillus oryzae Responsible for Substrate Recognition, Cleavage, Non-Specificity, and Inhibition. Plos One 11, doi:10.1371/journal.pone.0168832 (2016).

Kucera, J. et al. Comparative proteomic analysis of sulfur-oxidizing Acidithiobacillus ferrooxidans CCM 4253 cultures having lost the ability to couple anaerobic elemental sulfur oxidation with ferric iron reduction. Research in Microbiology 167, 587-594, doi:10.1016/j.resmic.2016.06.009 (2016).

Kylarova, S. et al. Cysteine residues mediate high-affinity binding of thioredoxin to ASK1. Febs Journal 283, 3821-3838, doi:10.1111/febs.13893 (2016).

Mikulecky, P. et al. Crystal structure of human interferon-gamma receptor 2 reveals the structural basis for receptor specificity. Acta Crystallogr. Sect. D-Struct. Biol. 72, 1017-1025, doi:10.1107/s2059798316012237 (2016).

Mullapudi, E. et al. Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3. Journal of Virology 90, 7628-7639, doi:10.1128/jvi.00746-16 (2016).

Mullapudi, E., Pridal, A., Palkova, L., de Miranda, J. R. & Plevka, P. Virion Structure of Israeli Acute Bee Paralysis Virus. Journal of Virology 90, 8150-8159, doi:10.1128/jvi.00854-16 (2016).

Lattova, E., Bryant, J., Skrickova, J., Zdrahal, Z. & Popovic, M. Efficient Procedure for N-Glycan Analyses and Detection of Endo H-Like Activity in Human Tumor Specimens. Journal of Proteome Research 15, 2777-2786, doi:10.1021/acs.jproteome.6b00346 (2016).

Lizal, T., Ustrnul, L., Necas, M. & Sindelar, V. Propanediurea-Based Molecular Clips Bind Halide Anions: An Insight into the Mechanism of Cucurbituril Formation. Journal of Organic Chemistry 81, 8906-8910, doi:10.1021/acs.joc.6b01602 (2016).

Novacek, J. et al. Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate. Proceedings of the National Academy of Sciences of the United States of America 113, 9351-9356, doi:10.1073/pnas.1605883113 (2016).

Pavelek, L., Ladanyi, V., Necas, M., Moravec, Z. & Wichterle, K. Synthesis and characterization of lanthanide complexes with a pentadentate triazine-based ligand. Polyhedron 119, 134-141, doi:10.1016/j.poly.2016.08.035 (2016).

Pesl, M. et al. Atomic force microscopy combined with human pluripotent stem cell derived cardiomyocytes for biomechanical sensing. Biosensors & Bioelectronics 85, 751-757, doi:10.1016/j.bios.2016.05.073 (2016).

Petrvalska, O. et al. Structural Insight into the 14-3-3 Protein-dependent Inhibition of Protein Kinase ASK1 (Apoptosis Signal-regulating kinase 1). Journal of Biological Chemistry 291, 20753-20765, doi:10.1074/jbc.M116.724310 (2016).

Phulwale, B. V., Mishra, S. K., Necas, M. & Mazal, C. Phenanthrylene-butadiynylene and Phenanthrylene-thienylene Macrocycles: Synthesis, Structure, and Properties. Journal of Organic Chemistry 81, 6244-6252, doi:10.1021/acs.joc.6b00814 (2016).

Sabin, C. et al. Structure of Aichi Virus 1 and Its Empty Particle: Clues to Kobuvirus Genome Release Mechanism. Journal of Virology 90, 10800-10810, doi:10.1128/jvi.01601-16 (2016).

Sedo, O. et al. Rapid assignment of malting barley varieties by matrix-assisted laser desorption-ionisation - Time-of-flight mass spectrometry. Food Chemistry 206, 124-130, doi:10.1016/j.foodchem.2016.03.056 (2016).

Stranava, M. et al. Structural characterization of the heme-based oxygen sensor, AfGcHK, its interactions with the cognate response regulator, and their combined mechanism of action in a bacterial two-component signaling system. Proteins-Structure Function and Bioinformatics 84, 1375-1389, doi:10.1002/prot.25083 (2016).

Ustrnul, L., Babiak, M., Kulhanek, P. & Sindelar, V. A Cucurbituril Derivative That Exhibits Cation-Modulated Self Assembly. Journal of Organic Chemistry 81, 6075-6080, doi:10.1021/acs.joc.6b01288 (2016).

Yadav, D. K. & Lukaysky, P. J. NMR solution structure determination of large RNA-protein complexes. Progress in Nuclear Magnetic Resonance Spectroscopy 97, 57-81, doi:10.1016/j.pnmrs.2016.10.001 (2016).

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