Successful Installation of World’s First 1.2 GHz NMR System Enables Novel Functional Structural Biology Research

13 May 2020

On May 4, 2020, Bruker Corporation announced the successful installation and customer acceptance of the world’s first Avance™ NEO 1.2 GHz NMR system at the CERM of the University of Florence. CERM is an Italian centre of the European research infrastructure in structural biology Instruct-ERIC. This new 1.2 GHz NMR system will enable CERM to perform novel research in functional structural biology of proteins and protein complexes. Ultra-high field (UHF) NMR is unique in its capabilities to study “difficult” protein systems and biological questions. These include the high-resolution structural and dynamic characterization of proteins, and their interactions in human living cells near physiological conditions. GHz-class NMR also enables improved research on intrinsically disordered proteins (IDPs). More details and potential applications overview can be found in a study Biomolecular NMR at 1.2 GHz by Lucia Banci & Claudio Luchinat and co-workers.

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