Successful Installation of World’s First 1.2 GHz NMR System Enables Novel Functional Structural Biology Research
On May 4, 2020, Bruker Corporation announced the successful installation and customer acceptance of the world’s first Avance™ NEO 1.2 GHz NMR system at the CERM of the University of Florence. CERM is an Italian centre of the European research infrastructure in structural biology Instruct-ERIC. This new 1.2 GHz NMR system will enable CERM to perform novel research in functional structural biology of proteins and protein complexes. Ultra-high field (UHF) NMR is unique in its capabilities to study “difficult” protein systems and biological questions. These include the high-resolution structural and dynamic characterization of proteins, and their interactions in human living cells near physiological conditions. GHz-class NMR also enables improved research on intrinsically disordered proteins (IDPs). More details and potential applications overview can be found in a study Biomolecular NMR at 1.2 GHz by Lucia Banci & Claudio Luchinat and co-workers.
New timsTOF Pro Mass Spectrometer installed at CEITEC.
New timsTOF Pro Mass Spectrometer (Bruker) has been installed at the Proteomics Core Facility, CEITEC MU. The new instrument brings another separation dimension (according collisional cross sections) in qualitative and quantitative characterization of complex protein samples as it is equipped by trapped ion mobility spectrometry (TIMS) module.
Emerging Topics in Biomolecular Magnetic Resonance – A new on-line lecture series
A new on-line lecture series on Emerging Topics in Biomolecular Magnetic Resonance, organized by Loren Andreas, Stefan Glöggler, Christian Griesinger, Mei Hong, Oscar Millet, Art Palmer, and Markus Zweckstetter, starts on Thursday, June 4, 2020.
Cryo-EM reaches yet another milestone – Comments on two recent cryo-EM atomic resolution studies
Two studies published during last two weeks have reported that single particle cryo-EM data can be now resolved to 1.20Å or 1.25Å, respectively. The groups of Sjors H.W. Scheres (LMB-MRC, Cambridge) and Holger Stark (MPI Göttingen) have for the first time shown that atomic resolution is attainable by single particle cryo-EM.
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