On May 4, 2020, Bruker Corporation announced the successful installation and customer acceptance of the world’s first Avance™ NEO 1.2 GHz NMR system at the CERM of the University of Florence. CERM is an Italian centre of the European research infrastructure in structural biology Instruct-ERIC. This new 1.2 GHz NMR system will enable CERM to perform novel research in functional structural biology of proteins and protein complexes. Ultra-high field (UHF) NMR is unique in its capabilities to study “difficult” protein systems and biological questions. These include the high-resolution structural and dynamic characterization of proteins, and their interactions in human living cells near physiological conditions. GHz-class NMR also enables improved research on intrinsically disordered proteins (IDPs). More details and potential applications overview can be found in a study Biomolecular NMR at 1.2 GHz by Lucia Banci & Claudio Luchinat and co-workers.
This is a reminder to apply for the Instruct-ERIC R&D Pilot Call - get funding of up to €15,000!
Closing 14:00 CEST on 15 April, the Instruct-ERIC R&D Funding Call invites early career researchers to submit proposals to access Instruct technology, equipment, and expertise from our 27 facilities across Europe for small scale pilot research projects in integrated structural biology.
Register now for the 32nd edition of the Instruct-ERIC Structure Meets Function webinar series, taking place on Zoom, 17 April at 11:00 CEST.
The latest webinar will have two speakers who have accessed the Instruct-ERIC facilities, expertise, and machinery via the ISIDORe project.
Talk 1: Nikitas Georgiou - National and Kapodistrian University of Athens
Title: Potential anti-inflammatory drugs
Talk 2: Séverine Padiolleau - Université de Technologie de Compiègne
Title: Identification of aptamers interacting with a protein target involved in lyme disease