EOSC Early Adopter Programme
The second call for the EOSC Early Adopter Programme is now open!
Workshop “Upconversion Immunoassays for the Diagnosis of Bee Diseases”, September 12, 2019
CEITEC Masaryk University, Institute of Macromolecular Chemistry, Czech Academy of Science and Regensburg University organize jointly a workshop on the diagnosis of bee diseases.
9th International Conference on Electron Tomography
The first announcement of 9th International Conference on Electron Tomography, organized by Utrecht University in Egmond See, The Netherlands, September 13-16, 2020, has been published.
The 5th Workshop of Structural Biology in the Helmholtz Association
The workshop will take place at the DKFZ in Heidelberg, from December 17 to December 18, 2019
Postdoc and PhD Positions in Biomolecular NMR spectroscopy - Selenko lab at the Weizmann Institute of Science
Postdoc and PhD positions in biomolecular NMR spectroscopy are available in the Selenko Lab at the Weizmann Institute of Science, Department of Biological Regulation.
PDB-Dev: A Prototype System for Depositing Integrative/Hybrid Structural Models
announced in 2017 contains now 22 officially released structures.
Reader’s Corner - literature to read, science to follow
As of July 2019, a new section Reader’s Corner - literature to read, science to follow has been added to our web.
eBIC Cryo-EM Sample preparation course 13th-15th Nov 2019
Registration for course at Diamond Light Source, UK is now open.
Reader's Corner Archive
Role of integrative structural biology in understanding transcriptional initiation
Role of integrative structural biology in understanding transcriptional initiation is discussed by Philip Robinson et. al. in a review, which presents a general background to integrative structural biology, describes of how it should be practically implemented, and shows how it has furthered our understanding of the biology of large transcriptional assemblies.
Frontiers in Cryo Electron Microscopy of Complex Macromolecular Assemblies
In this publication Sriram Subramaniam et. al. report on structural studies of G protein–coupled receptors, spliceosomes, and fibrillar specimens and illustrate the progress made by advanced cryo-EM methods.
The evolution of solution state NMR pulse sequences through the ‘eyes’ of triple-resonance spectroscopy
Lewis Kay in The evolution of solution state NMR pulse sequences through the ‘eyes’ of triple-resonance spectroscopy highlights how pulse sequence ‘engineering’ has evolved during past decades with the focus on liquid state NMR applications.
Principles for Integrative Structural Biology Studies
Guru of integrative structural biology computation Andrej Sali and Michale P. Rout summarize in the recent Cell Primer Principles for Integrative Structural Biology Studies.
Visualization of biological macromolecules at near-atomic resolution: cryo-electron microscopy comes of age
The topical review by Alok K. Mitra recapitulates developments and transformational advances of cryo-EM technology.
The expanding toolkit for structural biology: synchrotrons, X-ray lasers and cryo-EM
Samar Hasnain et. al. describe the steadily-expanding methodologies for atomic resolution studies in The expanding toolkit for structural biology: synchrotrons, X-ray lasers and cryo-EM. Of note is the following statistics: Despite the wealth of structures in the Protein Data Bank, a closer examination reveals that 89% of the structures, i.e. 126 994, are of proteins or complexes with a molecular weight of less than 160 kDa. Furthermore, only 4% of the deposited structures have a molecular weight in excess of 300 kDa.