Nanobiotechnology
Scanning probe microscopies for imaging of biological samples - tissue slices, cells, single biomolecules as nucleic acids and proteins. Studies of affinity interactions at the molecular level.
Key Equipment
- Scanning probe microscope - Ntegra Vita / Solaris (NTMDT)
- Atomic force microscope NanoWizzard3 (JPK)
- ForceRobot 300 (JPK)
- Automated system SolverNEXT (NTMDT)
- Ink-jet based deposition system S3 (Scienion)
Expertise
- Studies of biomolecules and other bio-objects at the molecular level using scanning probe techniques, i.e. atomic force microscopy (AFM) and related techniques (STM, SNOM, electrochemical variants), including combinations with optical microscopy (inverted, fluorescence, confocal)
- Production and bioconjugation of nanoparticles
- Advanced methods - nanolithograpy, nanomechanical manipulations, ink-jet based deposition
Open-access
- Preparation of samples for AFM
- Atomic force microscopic (AFM) imaging in contact and non-contact modes in dry and wet conditions, using bare and functionalised scanning tips for bioforce and biointeraction studies
- Combination of AFM with inverted optical microscopy, fluorescence and confocal microscopy, electrochemistry, near-field optical microscopy (SNOM)
- Nanomanipulations, nanolitography, nanopatterning and nanodeposition of biomolecules
Core Facility contact
Jan Přibyl - jan.pribyl@ceitec.muni.cz
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More information about Nanobiotechnology and related services you can find in document Equipement and services of CIISB .