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9 Mar 2021

Emerging Topics in Biomolecular Magnetic Resonance - Liliana Quintanar (Cinvestav, Mexico) and Nikolaos Sgourakis (University of Pennsylvania)

The series Emerging topics in Biomolecular Magnetic Resonance will continue on March 11th at 16:00 CEST with the following lecturers and topics:

  • Liliana Quintanar (Cinvestav, Mexico): Copper Ions and Protein Aggregation: From Amyloids in Diabetes to Non-Amyloids in Cataracts Disease
  • Nikolaos Sgourakis (University of Pennsylvania): Methyl resonance assignments, from methyl NOEs: Fact or Fiction?

8 Mar 2021

Upcoming session and workshop of the EOSC-Life Remote training series

As part of EOSC-Life Remote training series, on the 2nd of July 2021, a one-day workshop on ‘Hosting hybrid events’ will be organized. Please, save the date! More details will follow soon.

In relation to this workshop, you can take part in the next session of the series, on the 12th of March, 11-12 CET, to give the organizers input regarding your training needs and interests on the topic of organizing hybrid events.

22 Feb 2021

Upgrades at X-ray Diffraction and Bio-SAXS Core Facility

The universal, dual wavelength (Mo-Kα and Cu-Kα) diffractometer operated by X-ray Diffraction and Bio-SAXS Core Facility has been upgraded from the configuration Rigaku HighFlux HomeLab to the configuration Rigaku XtaLAB Synergy-DW™. The old X-ray detector Saturn 724+ based on CCD sensor Kodak KAF-4320E was replaced by a modern HPC (Hybrid Photon Counting) detector HyPix-6000HE and the old partial-chi axis goniometer AFC-11 by a fast high-precision 4-circle kappa goniometer. The effective performance of the diffractometer has increased approx 4 times, the new system is able to collect a complete diffraction datasets within a few (=1-3) hours, and the maximum resolution of diffraction data achievable before and after this upgrade has increased by about 0.3-0.5 Å.

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Newsletters

Reader's Corner Archive

11 May 2020

Visualizing an unseen enemy; mobilizing structural biology to counter COVID-19

Edward N. Baker from School of Biological Sciences, University of Auckland, New Zealand, has published an editorial in a number of IUCr Journals [see also Baker, E. N. (2020). IUCrJ. 7, 366–367; Baker, E. N. (2020). Acta Cryst. D76, 311–312] to highlight the work of structural biologists in fighting COVID-19. At the end of his short recollection he emphasizes: “My purpose in writing this editorial, however, is to applaud the energy and skill of the researchers, and their public spirit in sharing their results. And I take a vicarious pride in the fact that the discipline to which I have given my professional life – crystallography – has such an important role at a time of international crisis.”

15 Apr 2020

On the SARS-Cov-2 Inhibitor Track

To develop specific anti-coronavirus therapeutics and prophylactics, the molecular mechanism that underlies viral infection must first be defined. The recent study published in Cell Research solved the X-ray crystal structure of six-helical bundle (6-HB) core of the HR1 and HR2 domains in the SARS-CoV-2 S protein S2 subunit, revealing that several mutated amino acid residues in the HR1 domain may be associated with enhanced interactions with the HR2 domain, as compared to SARS-CoV.

7 Apr 2020

The 2020 Petr Sedmera Award

for the best published work in Nuclear Magnetic Resonance knows its winner. The competition is organized by the Czech Spectroscopic Society of Jan Marcus Marci and sponsored by the pharmaceutical company Teva. The awarded paper Quantitative Conformational Analysis of Functionally Important Electrostatic Interactions in the Intrinsically Disordered Region of Delta Subunit of Bacterial RNA Polymerase was published in Journal of the American Chemical Society by Lukáš Žídek and co-workers from CEITEC, Masaryk University. 

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