Biophysical techniques

Biophysical core research facilities offer a range of services, including investigations of biomolecular interactions, of structure, stability and conformation of DNA and proteins, determination of hydrodynamic radii, zeta potential and electrophoretic mobility of molecules, together with crystallization screens.

Key Equipment

    • Applied Photophysics circular dichroism (CD) spectrometer Chirascan Plus 
    • UV/visible spectrophotometer with temperature control Analytic Jena Specord 50 Plus 
    • BioRad ProteOn XPR36 interaction array instrument 
    • Monolith NT.150 microscale thermophoresis (MST) 
    • Monolith NT. LabelFree thermophoresis 
    • Prometheus NT.48 DSF assay 
    • Microcal iTC200 highly sensitive, low volume isothermal titration calorimeter 
    • Microcal VP-DSC highly sensitive differential scanning calorimeter 
    • Malvern Zetasizer Nano ZS90

Expertise

    • Characterisation of intermolecular interactions by calorimetry, surface plasmon resonance, CD spectrometry, microscale thermophoresis, light scattering

Open-access

  • Assisted use of all experimental equipment and “service” characterisation of interactions

Do you want to use this equipment or services?

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