HeliX+ Biosensor instrument from BRUKER was purchased to the Biophysical Techniques Facility of Centre of Molecular Structure.
It enables the study of molecular interactions, including kinetics, affinity and avidity and reveals conformational changes induced by analyte binding or buffer conditions with switchSENSE analysis. This DNA-lever based technology is particularly advantageous for molecules interacting with modifying oligonucleotides.
On November 27, 2025 Biophysical Techniques Facility of Centre of Molecular Structure will hold a workshop “Studying of molecular interactions by HeliX biosensor”. Will be represented instrument principle and applications, followed up by conducting of kinetic measurement on HeliX+ and protein-DNA conjugation using the proFIRE technology.
We are introducing Computer simulations for structural data interpretation as a new offering among CIISB’s service portfolio. The new service will run in pilot mode during 2026-2027 to evaluate the user interest and optimize the service offering in accordance with the user community needs.
The Institute of Biotechnology of the Academy of Sciences of the Czech Republic at the Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University in Vestec announces an open position:
Junior/medior backend developer in data management
We are looking for an enthusiast to join our team focused on management of biophysical data within the European project MOSBRI and the National Repository Platform.
We offer work connected to development of data management infrastructure for biophysical data in the frame of an international project at the Institute of Biotechnology in the BIOCEV Centre of Excellence.