The Biomolecular Interactions and Crystallography Core Facility of CEITEC MU is very happy to announce the installation of two cutting-edge instruments that will significantly boost our research capabilities to explore molecular properties with greater precision and depth.
The Fluorolog QM (Horriba) is a state-of-the-art modular spectrofluorometer designed for comprehensive fluorescence measurements. Its high sensitivity and flexibility make it ideal for a wide range of applications in life sciences. The system's modular design allows for the integration of various options of measurement - fluorescence anisotropy, time-resolved anisotropy with time-correlated single photon counting platform,and temperature-controlled fluorescence experiments. These options enable customized experimental setups to meet the specific needs of coming researchers. In addition to a standard cuvette, it is possible to use the ultralow volume cuvette with 1-5 μl volume which can be used for determination of quality steady state or lifetime data.
The Chirascan V100 (Applied Photophysics) is designed for circular dichroism (CD) studies, a well-established technique essential for investigating the properties of various molecules such as proteins, nucleic acids, and chiral drugs. This new instrument offers higher sensitivity and an improved signal-to-noise ratio, enabling more detailed measurements of changes in secondary and tertiary structure, as well as structural changes upon heating.
Both instruments were purchased from OP JAK project Innovation of Czech Infrastructure for Integrative Structural Biology (registration number: CZ.02.01.01/00/23_015/0008175)
For more information on the instrument details, terms of usage and reservations, check the CF website bic.ceitec.cz or contact the CF staff directly.
