Titan Krios transmission electron microscope at CEITEC equipped with phase plate and last generation direct electron detectors
Transmission electron microscope Titan Krios at Cryo-electron microscopy and tomography core facility CEITEC MU has been recently upgraded with phase plate, and two last generation direct electron detectors (FEI Falcon3EC, Gatan K2). Phase plate significantly increases contrast in cryo-electron microscopy data and allows to collect data at in-focus conditions. Moreover, increased contrast extends applicability of cryo-electron microscopy to high-resolution structural characterization of proteins and protein complexes which are around 100kDa in size. Both newly acquired direct electron detectors operate in electron counting mode, which provides superior image quality. Besides, the Gatan K2 detector position is behind the post-column energy filter and allows zero-loss imaging. Such application is primarily beneficial for imaging of thicker samples such as vitrified cells or focused ion beam micromachined cellular lamellas using cryo-electron tomography for the purpose of structural characterization of biomacromolecular complexes in situ. All upgrades were financed from the European Regional Development Fund-Project „CIISB4HEALTH“ (No. CZ.02.1.01/0.0/0.0/16_013/0001776).
Automatic sample changer and optic upgrade at the X-ray Diffraction and Bio-SAXS core facility at CEITEC MU
The automatic sample changer for BioSAXS Kratky camera system was installed and it is in operation.
POSTDOC: PROTEIN STRUCTURAL BIOLOGIST
We are seeking for a highly motivated scientist for EU-funded postdoctoral position inprotein structural biology for experimental team at Loschmidt Laboratories, Masaryk University, Brno, Czech Republic.
4th National Day of Large Research Infrastructures
The Ministry of Education, Youth and Sports of the Czech Republic and the Faculty of Mathematics and Physics of Charles University are honoured to invite you to take part in the 4th National Day of Large Research Infrastructures, to be held on 19th November 2019 in the premises of LINDAT/CLARIAH-CZlarge research infrastructure.
Instruct-ERIC International Access Call
We are delighted to announce the opening of the Instruct access call for International users.