The intention of the course is to provide practical training in important aspects of structural and dynamical analysis by NMR. The emphasis will be on setting up experiments on the spectrometer (optimizing parameters, pulse programs), on processing and analyzing the NMR data and on structure calculations in a hands-on fashion. It is impossible to also teach all the necessary theoretical background of modern NMR experiments in a few days. Therefore, the course is aimed at PhD students and postdocs who have some working knowledge of NMR theory, i.e. product operator formalism, and who understand the basic principles of NMR pulse sequences. Possible candidates should have of knowledge of NMR theory at the level of the book 'Protein NMR Spectroscopy' by Cavanagh et al. or similar.
Topics to be covered
- Pulse sequences for assignment and structural information: theory, practical set-up and use
- Multidimensional data processing
- Resonance assignment
- Relaxation: theory, experiments, data analysis
- Residual dipolar couplings: theory, experiments, data analysis
- Paramagnetic NMR: theory, experiments, data analysis
- In-cell NMR
- Structure calculation and evaluation
The application web site for the course is now open.
The application deadline is May 8, 2022.
Please see http://www.biozentrum.unibas.ch/embo22_nmr/ for further details.
Thank you for your interest.
Organizers EMBO Practical Course NMR 2022