The core facility now provides access to a new MALDI-TOF mass spectrometer, an Autoflex Speed device from Bruker Corporation. This instrument is suited mostly for the routine detection of peptides and intact proteins. The availability of this new device increases the throughput of analyzed samples, which was previously limited by the lengthy reservation times for accessing the 15T SolariX FT-ICR instrument.
Further, the new excimer laser for fast photo oxidative labeling of proteins will be used for monitoring of fast structural changes of proteins or protein-protein and protein-DNA complexes. A new UHLPC system will be installed in few days to increase the performance of analytes separation. The acquisition of new components was financed from European Regional Development Fund-Project „CIISB4HEALTH“ (No. CZ.02.1.01/0.0/0.0/16_013/0001776).