Organization changes of CIISB at the Institute of Biotechnology
The CIISB facilities at IBT have been undergoing the following organizational changes.
New timsTOF Pro Mass Spectrometer installed at CEITEC.
New timsTOF Pro Mass Spectrometer (Bruker) has been installed at the Proteomics Core Facility, CEITEC MU. The new instrument brings another separation dimension (according collisional cross sections) in qualitative and quantitative characterization of complex protein samples as it is equipped by trapped ion mobility spectrometry (TIMS) module.
Dual TIMS technology and PASEF (Parallel Accumulation Serial Fragmentation) acquisition method provide almost 100% duty cycle and up to 100 Hz acquisition speed without compromising sensitivity and mass resolution. It opens us a way to deeper insights in proteome even in case of low amounts of samples.
The purchase of the instrument was financed by MEYS CR from the Operational Programme: Research, Development and Education, the project „CIISB UP“ (No. CZ.02.1.01/0.0/0.0/18_046/0015974).