Organization changes of CIISB at the Institute of Biotechnology
The CIISB facilities at IBT have been undergoing the following organizational changes.
New Orbitrap Fusion Lumos Tribrid Mass Spectrometer installed at CEITEC
New Orbitrap Fusion Lumos Tribrid Mass Spectrometer (Thermo Scientific) has been installed at the Proteomics Core Facility, CEITEC MU. The new instrument equipped by three mass analyzers (a quadrupole, linear ion trap, an Orbitrap) and four fragmentation techniques (CID, HCD, ETD, EThcD) significantly improves our capabilities and flexibility in data dependent and data independent acquisition modes.
New technologies (such as Advanced Peak Determination or Synchronous Precursor Selection) bring large increase of the number of peptides and proteins identified and improve accuracy in quantitative studies using isobaric mass tags (TMT).
The purchase of the instrument was financed from the European Regional Development Fund-Project „CIISB4HEALTH“ (No. CZ.02.1.01/0.0/0.0/16_013/0001776).