New Orbitrap Fusion Lumos Tribrid Mass Spectrometer installed at CEITEC
New Orbitrap Fusion Lumos Tribrid Mass Spectrometer (Thermo Scientific) has been installed at the Proteomics Core Facility, CEITEC MU. The new instrument equipped by three mass analyzers (a quadrupole, linear ion trap, an Orbitrap) and four fragmentation techniques (CID, HCD, ETD, EThcD) significantly improves our capabilities and flexibility in data dependent and data independent acquisition modes.
New technologies (such as Advanced Peak Determination or Synchronous Precursor Selection) bring large increase of the number of peptides and proteins identified and improve accuracy in quantitative studies using isobaric mass tags (TMT).
The purchase of the instrument was financed from the European Regional Development Fund-Project „CIISB4HEALTH“ (No. CZ.02.1.01/0.0/0.0/16_013/0001776).
New state-of-the-art SAXSpoint 2.0 instrument installed at the Centre of Molecular Structure
The Petr Sedmera Award for 2018 was presented
Annually presented price for outstanding work published in the area of nuclear magnetic resonance in memory of Petr Sedmera, a renowned scientist who greatly contributed to the development of the field.
Nadrian C. Seeman: DNA, not Merely the Secret of Life
We build branched DNA species that can be joined using Watson-Crick base pairing to produce N-connected objects and lattices. We have used ligation to construct DNA topological targets, such as knots, polyhedral catenanes, Borromean rings and a Solomon's knot.
An Instruct/CIISB course took place at the CMS, IBT, Biocev on April 5 and 6, 2018.
This course/workshop allowed participants, with some prior knowledge and experience in macromolecular crystallography, to access the biophysical measurements section and the crystal handling/X-ray diffraction section of the Instruct CZ / CIISB CMS core facility for three practical work sessions.