New cryo-TEM at CEITEC MU
New mid-range 200 kV transmission electron microscope for cryo-electron microscopy has been installed at Cryo-electron microscopy and tomography core facility CEITEC Masaryk University.
Since October 1, 2018, a new cryo transmission electron microscope Talos Arctica (Thermo Scientific) is fully available to the facility users. The microscope is equipped with the Falcon3 EC direct electron detector and the Ceta camera. The instrument contains the Autoloader device which affords preservation of up to twelve samples inside the microscope. The microscope will be used for automated collection of data for single-particle analysis and structure determination of macromolecular complexes at < 4 A resolution. Moreover, the microscope will allow highly efficient screening and optimization of samples for cryo-electron microscopy. Data for structural characterization of biomacromolecular complexes in situ will be acquired using cryo-electron tomography. In addition, the system will permit applications of electron diffraction tomography for high-resolution structural studies of biomolecules in samples forming micro-crystals.
The purchase of the microscope was financed from the European Regional Development Fund-Project „CIISB4HEALTH“ (No. CZ.02.1.01/0.0/0.0/16_013/0001776).
CFs succeeded in getting support to organize workshop
New CIISB Newsletter just has been published
We proudly inform that Newsletter 2019 just has been published and is available on our web pages.
New microscope laboratory at the Cryo-electron microscopy core facility at CEITEC MU
The reconstruction of the Cryo-electron microscopy and tomography core facility laboratories which took place during autumn 2018 was finished in December.
PSB SYMPOSIUM "MACROMOLECULES IN ACTION"
The aim of this meeting is to illustrate how the big biological questions are resolved by combining key methods in structural biology (eg X-ray and neutron crystallography, cryo-EM, NMR and small angle scattering - SAXS and SANS)