New cryo-TEM at CEITEC MU
New mid-range 200 kV transmission electron microscope for cryo-electron microscopy has been installed at Cryo-electron microscopy and tomography core facility CEITEC Masaryk University.
Since October 1, 2018, a new cryo transmission electron microscope Talos Arctica (Thermo Scientific) is fully available to the facility users. The microscope is equipped with the Falcon3 EC direct electron detector and the Ceta camera. The instrument contains the Autoloader device which affords preservation of up to twelve samples inside the microscope. The microscope will be used for automated collection of data for single-particle analysis and structure determination of macromolecular complexes at < 4 A resolution. Moreover, the microscope will allow highly efficient screening and optimization of samples for cryo-electron microscopy. Data for structural characterization of biomacromolecular complexes in situ will be acquired using cryo-electron tomography. In addition, the system will permit applications of electron diffraction tomography for high-resolution structural studies of biomolecules in samples forming micro-crystals.
The purchase of the microscope was financed from the European Regional Development Fund-Project „CIISB4HEALTH“ (No. CZ.02.1.01/0.0/0.0/16_013/0001776).
Instruct-ERIC workshop on Computational Approaches in Integration of Structural Biology Techniques
On October 8 – 10, the Institute of Biotechnology of the Czech Academy of Sciences organised an Instruct – ERIC workshop on Computational Approaches in Integration of Structural Biology Techniques.
The 2019 Nobel Prize in Chemistry
Is awarded to John Goodenough, M. Stanley Whittingham and Akira Yoshino “for the development of lithium-ion batteries”.
The Nobel Prize in Physiology or Medicine 2019
is awarded jointly to William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza “for their discoveries of how cells sense and adapt to oxygen availability.”
The Nobel Prize in Physics 2019
is awarded ”for contributions to our understanding of the evolution of the universe and Earth’s place in the cosmos”, with one half to James Peebles “for theoretical discoveries in physical cosmology” and the other half jointly to Michel Mayor and Didier Queloz “for the discovery of an exoplanet orbiting a solar-type star.”