Instruct-ERIC is a European Research Infrastructure, providing researchers with access to high-end structural biology technologies and expertise, as well as enabling access to this equipment and expertise through an infrastructure distributed throughout Europe, with 15 members across the continent.
Structural Biology is currently in the middle of a revolution enabled by significant technology advances in recent years (direct electron detectors in EM, advances in synchrotron sources and detectors, XFELs, ultra-high field NMR, super-resolution cryo-light microscopy etc). For this reason, Instruct-ERIC is reviewing the structural biology capabilities within Europe to individuate possible updates in order to fully respond to the needs of the structural biology community.
It is thus important to have your feedback to support this activity: please fill in this short survey, and circulate it to your structural biology colleagues.
We are pleased to announce the expansion of our Protein Production Core Facility with the introduction of eukaryotic protein production. In addition to prokaryotic expression in E. coli, we now offer protein production in human embryonic kidney cells (HEK) and Sf9 insect cells.
In March, two new high resolution mass spectrometers were installed in our core facility thanks to CIISB project (CZ.02.01.01/00/23_015/0008175). First we upgraded our timsTOF Pro 2 instrument to timsTOF HT improving our performance in whole proteome analyses with faster scanning speed and a wider dynamic range. In second, Ultra 2 mass spectrometer was installed. This timsTOF instrument opens doors to deeper analysis of samples with limited amount of input material due to its ultimate sensitivity.