2017 Nobel Prize in Chemistry - Cryo-electron Microscopy
The Nobel Prize in Chemistry 2017 was awarded to Jacques Dubochet, Joachim Frank, and Richard Henderson "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution".
In 1990, Richard Henderson succeeded in using an electron microscope to generate a three-dimensional image of a protein at atomic resolution. This breakthrough proved the technology’s potential. Joachim Frank made the technology generally applicable. Between 1975 and 1986 he developed an image processing method in which the electron microscope’s fuzzy two-dimensional images are analysed and merged to reveal a sharp three-dimensional structure. Jacques Dubochet added water to electron microscopy. Liquid water evaporates in the electron microscope’s vacuum, which makes the biomolecules collapse. In the early 1980s, Dubochet succeeded in vitrifying water – he cooled water so rapidly that it solidified in its liquid form around a biological sample, allowing the biomolecules to retain their natural shape even in a vacuum. For more details look here: https://www.nobelprize.org/nobel_prizes/chemistry/laureates/2017/
4th National Day of Large Research Infrastructures
The Ministry of Education, Youth and Sports of the Czech Republic and the Faculty of Mathematics and Physics of Charles University are honoured to invite you to take part in the 4th National Day of Large Research Infrastructures, to be held on 19th November 2019 in the premises of LINDAT/CLARIAH-CZlarge research infrastructure.
Instruct-ERIC International Access Call
We are delighted to announce the opening of the Instruct access call for International users.
Prof Wolfgang Baumeister awarded the 2019 Ivano Bertini Award for outstanding contributions to structural biology
The Ivano Bertini Award is offered by Instruct to recognise a significant achievement in frontier research that utilises an integrative structural biology approach.
CFs succeeded in getting EU support to organize a workshop on the sample quality assessment