2017 Nobel Prize in Chemistry - Cryo-electron Microscopy
The Nobel Prize in Chemistry 2017 was awarded to Jacques Dubochet, Joachim Frank, and Richard Henderson "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution".
In 1990, Richard Henderson succeeded in using an electron microscope to generate a three-dimensional image of a protein at atomic resolution. This breakthrough proved the technology’s potential. Joachim Frank made the technology generally applicable. Between 1975 and 1986 he developed an image processing method in which the electron microscope’s fuzzy two-dimensional images are analysed and merged to reveal a sharp three-dimensional structure. Jacques Dubochet added water to electron microscopy. Liquid water evaporates in the electron microscope’s vacuum, which makes the biomolecules collapse. In the early 1980s, Dubochet succeeded in vitrifying water – he cooled water so rapidly that it solidified in its liquid form around a biological sample, allowing the biomolecules to retain their natural shape even in a vacuum. For more details look here: https://www.nobelprize.org/nobel_prizes/chemistry/laureates/2017/
eBIC Cryo-EM Sample preparation course 13th-15th Nov 2019
Registration for course at Diamond Light Source, UK is now open.
Extended Abstract Deadline for "New Frontiers in Structure-Based Drug Discovery" Conference
International conference on New Frontiers in Structure-Based Drug Discovery in Florence, Italy extended deadline for abstracts to July 15, 2019.
Call for proposals for 7th Instruct Internship Programme
Call for proposals for Instruct Internship Programme (for internships to be held in 2019-2020) is now open.
New combined AFM-Raman microscope at CEITEC MU
The new instrument equipped at the Nanobiotechnology Core Facility, CEITEC MU.