Structural Mass Spectrometry CF at BIOCEV acquired a new MALDI-TOF mass spectrometer
The structural mass spectrometry core facility at BIOCEV has expanded its equipment offer (and associated services) with several items.
The core facility now provides access to a new MALDI-TOF mass spectrometer, an Autoflex Speed device from Bruker Corporation. This instrument is suited mostly for the routine detection of peptides and intact proteins. The availability of this new device increases the throughput of analyzed samples, which was previously limited by the lengthy reservation times for accessing the 15T SolariX FT-ICR instrument.
Further, the new excimer laser for fast photo oxidative labeling of proteins will be used for monitoring of fast structural changes of proteins or protein-protein and protein-DNA complexes. A new UHLPC system will be installed in few days to increase the performance of analytes separation. The acquisition of new components was financed from European Regional Development Fund-Project „CIISB4HEALTH“ (No. CZ.02.1.01/0.0/0.0/16_013/0001776).
New state-of-the-art SAXSpoint 2.0 instrument installed at the Centre of Molecular Structure
The Peter Sedmer Award for 2018 was presented
Annually presented price for outstanding work published in the area of nuclear magnetic resonance in memory of Petr Sedmera, a renowned scientist who greatly contributed to the development of the field.
New Orbitrap Fusion Lumos Tribrid Mass Spectrometer installed at CEITEC
The new instrument equipped at the Proteomics Core Facility, CEITEC MU.
Nadrian C. Seeman: DNA, not Merely the Secret of Life
We build branched DNA species that can be joined using Watson-Crick base pairing to produce N-connected objects and lattices. We have used ligation to construct DNA topological targets, such as knots, polyhedral catenanes, Borromean rings and a Solomon's knot.