Karel Škubník has received a prestigious award ČESKÁ HLAVA (CZECH BRAINS)
On Sunday, December 3, 2017, Karel Škubník, a PhD student of Pavel Plevka, has received a prestigious award ČESKÁ HLAVA (CZECH BRAINS) in the category Doctorandus.
As a member of Pavel Plevka’s Research Group, which focuses on structural virology, Karel Škubník has been studying a three-dimensional structure of deformed wing (DWV) bee virus. Using the equipment and technology available in the CIISB Cryo-Electron Microscopy core facility at CEITEC, he has obtained a high-resolution data, which allowed him to solve the virion structures of DWV to a resolution of 3.1 A. The study showed that the virus surface is decorated with protruding globular extensions of capsid proteins. The protruding domains contain a putative catalytic site that is probably required for the entry of the virus into the host cell. Identifying the RNA binding and catalytic sites within the DWV virion offers prospects for the development of antiviral treatments. Results were published in PNAS and are described in more details in the section Research Highlights.
Nadrian C. Seeman: DNA, not Merely the Secret of Life
We build branched DNA species that can be joined using Watson-Crick base pairing to produce N-connected objects and lattices. We have used ligation to construct DNA topological targets, such as knots, polyhedral catenanes, Borromean rings and a Solomon's knot.
An Instruct/CIISB course took place at the CMS, IBT, Biocev on April 5 and 6, 2018.
This course/workshop allowed participants, with some prior knowledge and experience in macromolecular crystallography, to access the biophysical measurements section and the crystal handling/X-ray diffraction section of the Instruct CZ / CIISB CMS core facility for three practical work sessions.
XV. Discussions in Structural Molecular Biology and the 2nd User Meeting of the Czech Infrastructure for Integrative Structural Biology
In March, 2018, the Czech and Slovak community of structural biologists met at the "XV. Discussions in Structural Molecular Biology".
1st CEITEC Symposium on Recent Advances in Cryo-Electron Microscopy
Cryo-electron Microscopy and Tomography CEITEC Masaryk University has organized a one day symposium on recent developments in the field of cryo-electron microscopy on 18thApril 2018.