On Sunday, December 3, 2017, Karel Škubník, a PhD student of Pavel Plevka, has received a prestigious award ČESKÁ HLAVA (CZECH BRAINS) in the category Doctorandus.
As a member of Pavel Plevka’s Research Group, which focuses on structural virology, Karel Škubník has been studying a three-dimensional structure of deformed wing (DWV) bee virus. Using the equipment and technology available in the CIISB Cryo-Electron Microscopy core facility at CEITEC, he has obtained a high-resolution data, which allowed him to solve the virion structures of DWV to a resolution of 3.1 A. The study showed that the virus surface is decorated with protruding globular extensions of capsid proteins. The protruding domains contain a putative catalytic site that is probably required for the entry of the virus into the host cell. Identifying the RNA binding and catalytic sites within the DWV virion offers prospects for the development of antiviral treatments. Results were published in PNAS and are described in more details in the section Research Highlights.
This is a reminder to apply for the Instruct-ERIC R&D Pilot Call - get funding of up to €15,000!
Closing 14:00 CEST on 15 April, the Instruct-ERIC R&D Funding Call invites early career researchers to submit proposals to access Instruct technology, equipment, and expertise from our 27 facilities across Europe for small scale pilot research projects in integrated structural biology.
Register now for the 32nd edition of the Instruct-ERIC Structure Meets Function webinar series, taking place on Zoom, 17 April at 11:00 CEST.
The latest webinar will have two speakers who have accessed the Instruct-ERIC facilities, expertise, and machinery via the ISIDORe project.
Talk 1: Nikitas Georgiou - National and Kapodistrian University of Athens
Title: Potential anti-inflammatory drugs
Talk 2: Séverine Padiolleau - Université de Technologie de Compiègne
Title: Identification of aptamers interacting with a protein target involved in lyme disease