Publications written with support of CIISB

Recent publications

Modlitbova, P. et al. Short-term assessment of cadmium toxicity and uptake from different types of Cd-based Quantum Dots in the model plant Allium cepa L. Ecotoxicology and Environmental Safety 153, 23-31, doi:10.1016/j.ecoenv.2018.01.044 (2018).

Zahonova, K. et al. Extensive molecular tinkering in the evolution of the membrane attachment mode of the Rheb GTPase. Scientific Reports 8, 11, doi:10.1038/s41598-018-23575-0 (2018).

Benesik, M. et al. Role of SH3b binding domain in a natural deletion mutant of Kayvirus endolysin LysF1 with a broad range of lytic activity. Virus Genes 54, 130-139, doi:10.1007/s11262-017-1507-2 (2018).


CIISB research infrastructure project LM2015043 funded by MEYS CR is gratefully acknowledged for the financial support of the measurements at the CF [name of the CF].

All publications written with support of CIISB


Benesik, M. et al. Role of SH3b binding domain in a natural deletion mutant of Kayvirus endolysin LysF1 with a broad range of lytic activity. Virus Genes 54, 130-139, doi:10.1007/s11262-017-1507-2 (2018).

Doroshenko, I. et al. Hexanuclear iron(III) alpha-aminophosphonate: synthesis, structure, and magnetic properties of a molecular wheel. New Journal of Chemistry 42, 1931-1938, doi:10.1039/c7nj03606j (2018).

Dzatko, S. et al. Evaluation of the Stability of DNA i-Motifs in the Nuclei of Living Mammalian Cells. Angewandte Chemie-International Edition 57, 2165-2169, doi:10.1002/anie.201712284 (2018).

Evangelidis, T. et al. Automated NMR resonance assignments and structure determination using a minimal set of 4D spectra. Nature Communications 9, 13, doi:10.1038/s41467-017-02592-z (2018).

Farka, Z. et al. Prussian Blue Nanoparticles as a Catalytic Label in a Sandwich Nanozyme-Linked Immunosorbent Assay. Analytical Chemistry 90, 2348-2354, doi:10.1021/acs.analchem.7b04883 (2018).

Fiala, T., Sleziakova, K., Marsalek, K., Salvadori, K. & Sindelar, V. Thermodynamics of Halide Binding to a Neutral Bambusuril in Water and Organic Solvents. Journal of Organic Chemistry 83, 1903-1912, doi:10.1021/acs.joc.7b02846 (2018).

Fuzik, T. et al. Structure of tick-borne encephalitis virus and its neutralization by a monoclonal antibody. Nature Communications 9, 11, doi:10.1038/s41467-018-02882-0 (2018).

Garlikova, Z. et al. Generation of a Close-to-Native In Vitro System to Study Lung Cells-Extracellular Matrix Crosstalk. Tissue Engineering Part C-Methods 24, 1-13, doi:10.1089/ten.tec.2017.0283 (2018).

Haniewicz, P. et al. Molecular Mechanisms of Photoadaptation of Photosystem I Supercomplex from an Evolutionary Cyanobacterial/Algal Intermediate. Plant Physiology 176, 1433-1451, doi:10.1104/pp.17.01022 (2018).

Jancarikova, G. et al. Synthesis of alpha-L-Fucopyranoside-Presenting Glycoclusters and Investigation of Their Interaction with Photorhabdus asymbiotica Lectin (PHL). Chemistry-a European Journal 24, 4055-4068, doi:10.1002/chem.201705853 (2018).

Jandova, Z., Trosanova, Z., Weisova, V., Oostenbrink, C. & Hritz, J. Free energy calculations on the stability of the 14-3-3 zeta protein. Biochimica Et Biophysica Acta-Proteins and Proteomics 1866, 442-450, doi:10.1016/j.bbapap.2017.11.012 (2018).

Modlitbova, P. et al. Comparative investigation of toxicity and bioaccumulation of Cd-based quantum dots and Cd salt in freshwater plant Lemna minor L. Ecotoxicology and Environmental Safety 147, 334-341, doi:10.1016/j.ecoenv.2017.08.053 (2018). 

Modlitbova, P. et al. Short-term assessment of cadmium toxicity and uptake from different types of Cd-based Quantum Dots in the model plant Allium cepa L. Ecotoxicology and Environmental Safety 153, 23-31, doi:10.1016/j.ecoenv.2018.01.044 (2018).

Novotny, J. et al. Hyperfine Effects in Ligand NMR: Paramagnetic Ru(III) Complexes with 3 Substituted Pyridines. Inorganic Chemistry 57, 641-652, doi:10.1021/acs.inorgchem.7b02440 (2018).

Rozbesky, D. et al. Impact of Chemical Cross-Linking on Protein Structure and Function. Analytical Chemistry 90, 1104-1113, doi:10.1021/acs.analchem.7b02863 (2018).

Skerlova, J. et al. Crystal structure of native beta-N-acetylhexosaminidase isolated from Aspergillus oryzae sheds light onto its substrate specificity, high stability, and regulation by propeptide. Febs Journal 285, 580-598, doi:10.1111/febs.14360 (2018).

Stafkova, J. et al. Dynamic secretome of Trichomonas vaginalis: Case study of beta-amylasesMolecular & Cellular Proteomics 17, 304-320, doi:10.1074/mcp.RA117.000434 (2018).

Yawer, M. A., Sleziakova, K., Pavlovec, L. & Sindelar, V. Bambusurils. Bearing Nitro Groups and Their Further Modifications. European Journal of Organic Chemistry, 41-47, doi:10.1002/ejoc.201701329 (2018).

Zahonova, K. et al. Extensive molecular tinkering in the evolution of the membrane attachment mode of the Rheb GTPase. Scientific Reports 8, 11, doi:10.1038/s41598-018-23575-0 (2018).


Bhat, S. S., Revankar, V. K., Khan, A., Pinjari, R. V. & Necas, M. Luminescent Ruthenium(II) Polypyridyl Complexes as Nonviral Carriers for DNA Delivery. Chemistry-an Asian Journal 12, 254-264, doi:10.1002/asia.201601515 (2017).

Blaha, J. et al. High-level expression and purification of soluble form of human natural killer cell receptor NKR-P1 in HEK293S GnTI(-) cells. Protein Expression and Purification 140, 36-43, doi:10.1016/j.pep.2017.07.016 (2017).

Bocanek, O., Sedo, O., Pekar, S. & Zdrahal, Z. Evaluation of sample preparation protocols for spider venom profiling by MALDI-TOF MS. Toxicon 133, 18-25, doi:10.1016/j.toxicon.2017.04.008 (2017).

Brabencova, S. et al. Variations of Histone Modification Patterns: Contributions of Inter-plant Variability and Technical Factors. Frontiers in Plant Science 8, 12, doi:10.3389/fpls.2017.02084 (2017).

Buchtelova, H. et al. pH-Responsive Hybrid Organic-Inorganic Ruthenium Nanoparticles for Controlled Release of Doxorubicin. Particle & Particle Systems Characterization 34, 9, doi:10.1002/ppsc.201700289 (2017).

Chalupa, D. et al. Enantioselective Synthesis of Cephalimysins B and C. Organic Letters 19, 750-753, doi:10.1021/acs.orglett.6b03373 (2017).

Chamradova, I. et al. The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer. Colloid and Polymer Science 295, 107-115, doi:10.1007/s00396-016-3983-7 (2017).

Csavas, M. et al. Tri- and tetravalent mannoclusters cross-link and aggregate BC2L-A lectin from Burkholderia cenocepaciaCarbohydrate Research 437, 1-8, doi:10.1016/j.carres.2016.11.008 (2017).

Dostalova, S. et al. Apoferritin as an ubiquitous nanocarrier with excellent shelf life. International Journal of Nanomedicine 12, 2265-2278, doi:10.2147/ijn.s130267 (2017).

Farka, Z., Mickert, M. J., Hlavacek, A., Skladal, P. & Gorris, H. H. Single Molecule Upconversion-Linked Immunosorbent Assay with Extended Dynamic Range for the Sensitive Detection of Diagnostic Biomarkers. Analytical Chemistry 89, 11825-11830, doi:10.1021/acs.analchem.7b03542 (2017).

Fiala, T. et al. Bambusuril as a One-Electron Donor for Photoinduced Electron Transfer to Methyl Viologen in Mixed Crystals. Journal of the American Chemical Society 139, 2597-2603, doi:10.1021/jacs.6b08589 (2017).

Gajarsky, M. et al. Structure of a Stable G-Hairpin. Journal of the American Chemical Society 139, 3591-3594, doi:10.1021/jacs.6b10786 (2017).

Garlikova, Z. et al. Generation of a Close-to-Native In Vitro System to Study Lung Cells-Extracellular Matrix Crosstalk. Tissue Engineering Part C-Methods, 13, doi:10.1089/ten.tec.2017.0283 (2017).

Graf, M. et al. Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions. Nucleic Acids Research 45, 2887-2896, doi:10.1093/nar/gkw1272 (2017).

Grochalova, M. et al. Deep coverage of the beer proteome. Journal of Proteomics 162, 119-124, doi:10.1016/j.jprot.2017.05.001 (2017).

Hamzehee, F., Pourayoubi, M., Necas, M. & Choquesillo-Lazarte, D. Extensive analysis of N-H center dot center dot center dot O hydrogen bonding in four classes of phosphorus compounds: a combined experimental and database study. Acta Crystallographica Section C-Structural Chemistry 73, 287-+, doi:10.1107/s2053229617001516 (2017).

Havel, V., Babiak, M. & Sindelar, V. Modulation of Bambusuril Anion Affinity in Water. Chemistry-a European Journal 23, 8963-8968, doi:10.1002/chem.201701316 (2017).

Hlavacek, A. et al. Rapid single-step upconversion-linked immunosorbent assay for diclofenac. Microchimica Acta 184, 4159-4165, doi:10.1007/s00604-017-2456-0 (2017).

Huter, P. et al. Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P. Molecular Cell 68, 515-+, doi:10.1016/j.molcel.2017.10.014 (2017).

Hylse, O. et al. A Concise Synthesis of Forskolin. Angewandte Chemie-International Edition 56, 12586-12589, doi:10.1002/anie.201706809 (2017).

Ilgova, J. et al. A novel type I cystatin of parasite origin with atypical legumain-binding domain. Scientific Reports 7, 12, doi:10.1038/s41598-017-17598-2 (2017).

Jancarikova, G. et al. Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity. Plos Pathogens 13, 28, doi:10.1371/journal.ppat.1006564 (2017).

Jansen, S. et al. Quantitative mapping of microtubule-associated protein 2c (MAP2c) phosphorylation and regulatory protein 14-3-3 zeta-binding sites reveals key differences between MAP2c and its homolog Tau. Journal of Biological Chemistry 292, 6715-6727, doi:10.1074/jbc.M116.771097 (2017).

Jasnovidova, O. et al. Structure and dynamics of the RNAPII CTDsome with Rtt103. Proceedings of the National Academy of Sciences of the United States of America 114, 11133-11138, doi: doi:10.1073/pnas.1712450114

Jasnovidova, O., Krejcikova, M., Kubicek, K. & Stefl, R. Structural insight into recognition of phosphorylated threonine-4 of RNA polymerase II C-terminal domain by Rtt103p. Embo Reports 18, 906-913, doi:10.15252/embr.201643723 (2017).

Jelinkova, K. et al. Cubane Arrives on the Cucurbituril SceneOrganic Letters 19, 2698-2701, doi:10.1021/acs.orglett.7b01029 (2017).

Kacirova, M., Novacek, J., Man, P., Obsilova, V. & Obsil, T. Structural Basis for the 14-3-3 Protein-Dependent Inhibition of Phosducin Function. Biophysical Journal 112, 1339-1349, doi:10.1016/j.bpj.2017.02.036 (2017).

Kalabova, D. et al. Human procaspase-2 phosphorylation at both S139 and S164 is required for 14-3-3 binding. Biochemical and Biophysical Research Communications 493, 940-945, doi:10.1016/j.bbrc.2017.09.116 (2017).

Kalynych, S., Fuzik, T., Pridal, A., de Miranda, J. & Plevka, P. Cryo-EM study of slow bee paralysis virus at low pH reveals iflavirus genome release mechanism. Proceedings of the National Academy of Sciences of the United States of America 114, 598-603, doi:10.1073/pnas.1616562114 (2017).

Kodedova, M. & Sychrova, H. Synthetic antimicrobial peptides of the halictines family disturb the membrane integrity of Candida cells. Biochimica Et Biophysica Acta-Biomembranes 1859, 1851-1858, doi:10.1016/j.bbamem.2017.06.005 (2017).

Kovalenko, A. et al. Adamantane substitutions: a path to high-performing, soluble, versatile and sustainable organic semiconducting materials. Journal of Materials Chemistry C 5, 4716-4723, doi:10.1039/c6tc05076j (2017).

Lousa, P., Nedozralova, H., Zupa, E., Novacek, J. & Hritz, J. Phosphorylation of the regulatory domain of human tyrosine hydroxylase 1 monitored using non-uniformly sampled NMR. Biophysical Chemistry 223, 25-29, doi:10.1016/j.bpc.2017.01.003 (2017).

Maier, L. et al. Diastereoselective Flexible Synthesis of Carbocyclic C-Nucleosides. Journal of Organic Chemistry 82, 3382-3402, doi:10.1021/acs.joc.6b02594 (2017).

Malatinsky, T. et al. Reversal of Stereoselectivity in Cycloadditions of Five-Membered Cyclic Nitrones Derived from Hexoses. European Journal of Organic Chemistry, 1086-1098, doi:10.1002/ejoc.201601488 (2017).

Mullapudi, E., Fuzik, T., Pridal, A. & Plevka, P. Cryo-electron Microscopy Study of the Genome Release of the Dicistrovirus Israeli Acute Bee Paralysis Virus. Journal of Virology 91, 12, doi:10.1128/jvi.02060-16 (2017).

Nejdl, L. et al. Platinum nanoparticles induce damage to DNA and inhibit DNA replicationPlos One 12, 19, doi:10.1371/journal.pone.0180798 (2017).

Nemec, A., Radolfova-Krizova, L., Maixnerova, M. & Sedo, O. Acinetobacter colistiniresistens sp nov (formerly genomic species 13 sensu Bouvet and Jeanjean and genomic species 14 sensu Tjernberg and Ursing), isolated from human infections and characterized by intrinsic resistance to polymyxins. International Journal of Systematic and Evolutionary Microbiology 67, 2134-2141, doi:10.1099/ijsem.0.001903 (2017).

Otevrel, J. & Bobal, P. Diamine-Tethered Bis(thiourea) Organocatalyst for Asymmetric Henry ReactionJournal of Organic Chemistry 82, 8342-8358, doi:10.1021/acs.joc.7b00079 (2017).

Otrusinova, O. et al. Conformational dynamics are a key factor in signaling mediated by the receiver domain of a sensor histidine kinase from Arabidopsis thaliana. Journal of Biological Chemistry 292, 17525-17540, doi:10.1074/jbc.M117.790212 (2017).

Pekarik, V. et al. Visualization of stable ferritin complexes with palladium, rhodium and iridium nanoparticles detected by their catalytic activity in native polyacrylamide gels. Dalton Transactions 46, 13690-13694, doi:10.1039/c7dt02818k (2017).

Prochazkova, I. et al. Targeted proteomics driven verification of biomarker candidates associated with breast cancer aggressiveness. Biochimica Et Biophysica Acta-Proteins and Proteomics 1865, 488-498, doi:10.1016/j.bbapap.2017.02.012 (2017).

Rais, R. et al. Discovery of a para-Acetoxy-benzyl Ester Prodrug of a Hydroxamate-Based Glutamate Carboxypeptidase II Inhibitor as Oral Therapy for Neuropathic Pain. Journal of Medicinal Chemistry 60, 7799-7809, doi:10.1021/acs.jmedchem.7b00825 (2017).

Rivera-Calzada, A. et al. The Structure of the R2TP Complex Defines a Platform for Recruiting Diverse Client Proteins to the HSP90 Molecular Chaperone SystemStructure 25, 1145-+, doi:10.1016/j.str.2017.05.016 (2017).

Salasova, A. et al. A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway. Molecular Neurodegeneration 12, 19, doi:10.1186/s13024-017-0193-9 (2017).

Schmidt, J. M. et al. A New Two-Step Chromatographic Procedure for Fractionation of Potato Proteins with Potato Fruit Juice and Spray-Dried Protein as Source Materials. Food and Bioprocess Technology 10, 1946-1958, doi:10.1007/s11947-017-1966-4 (2017).

Slany, M., Oppelt, J. & Cincarova, L. Formation of Staphylococcus aureus Biofilm in the Presence of Sublethal Concentrations of Disinfectants Studied via a Transcriptomic Analysis Using Transcriptome Sequencing (RNA-seq). Applied and Environmental Microbiology 83, 13, doi:10.1128/aem.01643-17 (2017).

Spurny, R. et al. Virion Structure of Black Queen Cell Virus, a Common Honeybee Pathogen. Journal of Virology 91, 14, doi:10.1128/jvi.02100-16 (2017).

Srb, P. et al. Triple resonance NMR relaxation experiments for studies of intrinsically disordered proteins. Journal of Biomolecular Nmr 69, 133-146, doi:10.1007/s10858-017-0138-1 (2017).

Styskalik, A., Babiak, M., Machac, P., Relichova, B. & Pinkas, J. New Adamantane-like Silicophosphate Cage and Its Reactivity toward Tris(pentafluorophenyl)borane. Inorganic Chemistry 56, 10699-10705, doi:10.1021/acs.inorgchem.7b01572 (2017).

Torti, E. et al. Supramolecular Storage and Controlled Photorelease of an Oxidizing Agent using a Bambusuril Macrocycle. Chemistry-a European Journal 23, 16768-16772, doi:10.1002/chem.201704948 

Uhlikova, H. et al. MAMP (microbe-associated molecular pattern)-induced changes in plasma membrane-associated proteins. Journal of Plant Physiology 210, 51-57, doi:10.1016/j.jplph.2016.12.005 (2017).

Weimann, I., Feller, J. & Zak, Z. Phase Equilibria in the System CuO-NiO-P4O10 and Synthesis, Crystal Structure, and Characterization of the New Copper Nickel Oxide Phosphate Cu3NiO(PO4)(2)Zeitschrift Fur Anorganische Und Allgemeine Chemie 643, 299-305, doi:10.1002/zaac.201600403 (2017).

Zachrdla, M. et al. Solution structure of domain 1.1 of the sigma(A) factor from Bacillus subtilis is preformed for binding to the RNA polymerase coreJournal of Biological Chemistry 292, 11610-11617, doi:10.1074/jbc.M117.784074 (2017).

Zadorozhny, K. et al. Fanconi-Anemia-Associated Mutations Destabilize RAD51 Filaments and Impair Replication Fork Protection. Cell Reports 21, 333-340, doi:10.1016/j.celrep.2017.09.062 (2017).

Zeman, M. et al. Staphylococcus sciuri bacteriophages double-convert for staphylokinase and phospholipase, mediate interspecies plasmid transduction, and package mecA geneScientific Reports 7, 11, doi:10.1038/srep46319 (2017



Costanzo, G. et al. Non-Enzymatic Oligomerization of 3 ', 5 ' Cyclic AMP. Plos One 11, 14, doi:10.1371/journal.pone.0165723 (2016).

Hafidh, S. et al. Quantitative proteomics of the tobacco pollen tube secretome identifies novel pollen tube guidance proteins important for fertilization. Genome Biology 17, 29, doi:10.1186/s13059-016-0928-x (2016).

Kucera, J. et al. Comparative proteomic analysis of sulfur-oxidizing Acidithiobacillus ferrooxidans CCM 4253 cultures having lost the ability to couple anaerobic elemental sulfur oxidation with ferric iron reduction. Research in Microbiology 167, 587-594, doi:10.1016/j.resmic.2016.06.009 (2016).

Kylarova, S. et al. Cysteine residues mediate high-affinity binding of thioredoxin to ASK1. Febs Journal 283, 3821-3838, doi:10.1111/febs.13893 (2016).

Lattova, E., Bryant, J., Skrickova, J., Zdrahal, Z. & Popovic, M. Efficient Procedure for N-Glycan Analyses and Detection of Endo H-Like Activity in Human Tumor Specimens. Journal of Proteome Research 15, 2777-2786, doi:10.1021/acs.jproteome.6b00346 (2016).

Lizal, T., Ustrnul, L., Necas, M. & Sindelar, V. Propanediurea-Based Molecular Clips Bind Halide Anions: An Insight into the Mechanism of Cucurbituril Formation. Journal of Organic Chemistry 81, 8906-8910, doi:10.1021/acs.joc.6b01602 (2016).

Novacek, J. et al. Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate. Proceedings of the National Academy of Sciences of the United States of America 113, 9351-9356, doi:10.1073/pnas.1605883113 (2016).

Pavelek, L., Ladanyi, V., Necas, M., Moravec, Z. & Wichterle, K. Synthesis and characterization of lanthanide complexes with a pentadentate triazine-based ligand. Polyhedron 119, 134-141, doi:10.1016/j.poly.2016.08.035 (2016).

Phulwale, B. V., Mishra, S. K., Necas, M. & Mazal, C. Phenanthrylene-butadiynylene and Phenanthrylene-thienylene Macrocycles: Synthesis, Structure, and Properties. Journal of Organic Chemistry 81, 6244-6252, doi:10.1021/acs.joc.6b00814 (2016).

Sedo, O. et al. Rapid assignment of malting barley varieties by matrix-assisted laser desorption-ionisation - Time-of-flight mass spectrometry. Food Chemistry 206, 124-130, doi:10.1016/j.foodchem.2016.03.056 (2016).

Stranava, M. et al. Structural characterization of the heme-based oxygen sensor, AfGcHK, its interactions with the cognate response regulator, and their combined mechanism of action in a bacterial two-component signaling system. Proteins-Structure Function and Bioinformatics 84, 1375-1389, doi:10.1002/prot.25083 (2016).

Ustrnul, L., Babiak, M., Kulhanek, P. & Sindelar, V. A Cucurbituril Derivative That Exhibits Cation-Modulated Self Assembly. Journal of Organic Chemistry 81, 6075-6080, doi:10.1021/acs.joc.6b01288 (2016).

Yadav, D. K. & Lukaysky, P. J. NMR solution structure determination of large RNA-protein complexes. Progress in Nuclear Magnetic Resonance Spectroscopy 97, 57-81, doi:10.1016/j.pnmrs.2016.10.001 (2016).

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